Date published: 2025-12-15

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2-Hydroxyhexanoic acid (CAS 6064-63-7)

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Alternate Names:
DL-α-Hydroxycaproic acid
CAS Number:
6064-63-7
Purity:
98%
Molecular Weight:
132.16
Molecular Formula:
C6H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxyhexanoic acid is a carboxylic acid derivative that occurs naturally in plants, animals, and fungi. This compound serves as a vital intermediate in the synthesis of various compounds. Notably, it acts as a foundational component for creating derivatives like 2-hydroxycaproic acid esters, 2-hydroxyhexanoic acid esters, and 2-hydroxycaproic acid amides. Moreover, it finds application as a reagent in organic synthesis.


2-Hydroxyhexanoic acid (CAS 6064-63-7) References

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  2. Weakening of salmonella with selected microbial metabolites of berry-derived phenolic compounds and organic acids.  |  Alakomi, HL., et al. 2007. J Agric Food Chem. 55: 3905-12. PMID: 17439151
  3. Plant and animal glycolate oxidases have a common eukaryotic ancestor and convergently duplicated to evolve long-chain 2-hydroxy acid oxidases.  |  Esser, C., et al. 2014. Mol Biol Evol. 31: 1089-101. PMID: 24408912
  4. 2-hydroxycaproate predicts cardiovascular mortality in patients with atherosclerotic disease.  |  Cardellini, M., et al. 2018. Atherosclerosis. 277: 179-185. PMID: 29958653
  5. Enantioselective biocatalytic formal α-amination of hexanoic acid to l-norleucine.  |  Dennig, A., et al. 2018. Org Biomol Chem. 16: 8030-8033. PMID: 30334043
  6. Catalytic ozonation of 2, 2'-methylenebis (4-methyl-6-tert-butylphenol) over nano-Fe3O4@cow dung ash composites: Optimization, toxicity, and degradation mechanisms.  |  Ma, C., et al. 2020. Environ Pollut. 265: 114597. PMID: 32806439
  7. Organic acid shift reagents for the discrimination of carbohydrate isobars by ion mobility-mass spectrometry.  |  McKenna, KR., et al. 2021. Analyst. 145: 8008-8015. PMID: 33052364
  8. Rapid differentiation of enterotoxigenic Escherichia coli that produce heat-stable and heat-labile toxins by frequency-pulsed electron capture gas-liquid chromatography analysis of diarrheal stool specimens.  |  Brooks, JB., et al. 1984. J Clin Microbiol. 20: 1145-53. PMID: 6394617
  9. Synthesis of 2-hydroxy acid from 2-amino acid by Clostridium butyricum.  |  Khelifa, N., et al. 1998. Bioorg Med Chem Lett. 8: 3429-34. PMID: 9873747
  10. The preparation and characterization of some organic complexes of germanium  |  E.R. Clark a b, N.H. Davies a b, A.V. Jones a b. 1965. Journal of Inorganic and Nuclear Chemistry. 27: 1611-1617.
  11. Direct resolution of enantiomers of 2- and 3-hydroxy acid alkyl esters by fused-silica capillary gas chromatography  |  Bernhard Koppenhoefer ∗, Hans Allmendinger, Graeme J. Nicholson, Ernst Bayer. 1983. Journal of Chromatography A. 260: 63-73.
  12. Lipase-catalysed reactions of chiral hydroxyacid esters: competition of esterification and transesterification  |  Karl-Heinz Engel, Martina Bohnen, Martina Dobe. 1991. Enzyme and Microbial Technology. 13: 655-660.
  13. Solubilities of lactic acid and 2-hydroxyhexanoic acid in supercritical CO2  |  Jacek Gregorowicz. 1999. Fluid Phase Equilibria. 166: 39-46.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxyhexanoic acid, 1 g

sc-209200
1 g
$153.00