Molecular structure of 2-Bromoacetophenone, CAS Number: 70-11-1
2-Bromoacetophenone (CAS 70-11-1)
Alternate Names:
Phenacyl bromide; ω-Bromoacetophenone
Application:
2-Bromoacetophenone is an irreversible human liver aldehyde dehydrogenase isoenzyme inactivator
CAS Number:
70-11-1
Purity:
≥97%
Molecular Weight:
199.04
Molecular Formula:
C8H7BrO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Bromoacetophenone functions as an electrophilic aromatic substitution reagent in organic synthesis. It acts as an acylating agent, reacting with nucleophiles such as amines and phenols to form ketones and esters, respectively. The mechanism of action involves the bromine atom serving as a leaving group, facilitating the substitution reaction on the aromatic ring. 2-Bromoacetophenone′s mechanism of action involves the activation of the aromatic ring, allowing for the introduction of acetyl groups in a controlled manner. 2-Bromoacetophenone plays a role in the modification of organic molecules, enabling the synthesis of diverse compounds for research and development purposes.
2-Bromoacetophenone (CAS 70-11-1) References
- Selective derivatization of cytosine and methylcytosine moieties with 2-bromoacetophenone for submicrogram DNA methylation analysis by reversed phase HPLC with spectrofluorimetric detection. | Torres, AL., et al. 2011. Anal Chem. 83: 7999-8005. PMID: 21905673
- Determination of berberine-upregulated endogenous short-chain fatty acids through derivatization by 2-bromoacetophenone. | Ma, SR., et al. 2019. Anal Bioanal Chem. 411: 3191-3207. PMID: 30972469
- Synthesis of Potent Anticancer Substituted 5-Benzimidazol-2-amino Thiazoles Controlled by Bifunctional Hydrogen Bonding under Microwave Irradiations. | Bangade, VM., et al. 2021. J Org Chem. 86: 6056-6065. PMID: 33872008
- Stepwise synthesis and catalysis in C-S cross-coupling of pyridine-functionalized N-heterocyclic carbene nickel(II) complexes by mechanochemistry. | Cui, X., et al. 2022. Dalton Trans. 51: 4377-4385. PMID: 35191915
- Solid-phase reactive chromatography (SPRC): a sustainable method for the synthesis of benzimidazol-diphenyl-2-imino-thiazolidine-4-ols (hemiaminals) which are active against lung cancer. | Bangade, VM., et al. 2021. RSC Adv. 11: 2320-2324. PMID: 35424177
- Visible-light-driven cascade radical cyclization toward the synthesis of α-carbonyl alkyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-one derivatives. | Liu, J., et al. 2021. RSC Adv. 11: 29372-29375. PMID: 35479569
- Study of Novel Furocoumarin Derivatives on Anti-Vitiligo Activity, Molecular Docking and Mechanism of Action. | Niu, C., et al. 2022. Int J Mol Sci. 23: PMID: 35887323
- The Glycine-Glucolipid of Alcanivorax borkumensis Is Resident to the Bacterial Cell Wall. | Cui, J., et al. 2022. Appl Environ Microbiol. 88: e0112622. PMID: 35938787
- Synthesis, Antiproliferative Evaluation and QSAR Analysis of Novel Halogen- and Amidino-Substituted Benzothiazoles and Benzimidazoles. | Rep Kaulić, V., et al. 2022. Int J Mol Sci. 23: PMID: 36555479
- Synthesis, ADMET Prediction, and Antitumor Profile of Phenoxyhydrazine- 1,3-thiazoles Derivatives. | de Siqueira, LRP., et al. 2023. Curr Top Med Chem. 23: 265-282. PMID: 36573055
- Sustainable Ir-Photoredox Catalysis by Means of Heterogenization. | Lindroth, R., et al. 2022. ACS Org Inorg Au. 2: 427-432. PMID: 36855667
- Selective quantitative N-functionalization of unprotected α-amino acids using NHC-Ir(III) catalyst. | Saavedra, B., et al. 2023. STAR Protoc. 4: 102147. PMID: 36920910
- Recent Advances and Challenges in Long Wavelength Sensitive Cationic Photoinitiating Systems. | Zhang, L., et al. 2023. Polymers (Basel). 15: PMID: 37299323
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Bromoacetophenone, 5 g | sc-254176 | 5 g | $34.00 | |||
2-Bromoacetophenone, 100 g | sc-254176A | 100 g | $107.00 |