Molecular structure of 2,5-Dihydrofuran, CAS Number: 1708-29-8
2,5-Dihydrofuran (CAS 1708-29-8)
CAS Number:
1708-29-8
Molecular Weight:
70.09
Molecular Formula:
C4H6O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2,5-Dihydrofuran is a chemical compound that functions as a reactive intermediate in various organic synthesis reactions. It acts as a diene in Diels-Alder reactions, participating in cycloaddition reactions with dienophiles to form complex organic compounds. Mode of action involves its ability to undergo cycloaddition reactions with electron-deficient dienophiles, leading to the formation of fused ring systems and other structurally diverse molecules. In this, 2,5-dihydrofuran serves as a versatile building block for the construction of complex organic molecules with potential applications in materials science and agrochemicals. Its reactivity and ability to undergo selective transformations make it useful for the synthesis of diverse chemical structures, contributing to the development of new compounds with unique properties and potential applications in various development endeavors.
2,5-Dihydrofuran (CAS 1708-29-8) References
- An efficient synthesis of 2,5-dihydrofuran-fused bicyclic skeletons via the Pd(II)-catalyzed tandem-cyclization reaction of 1,omega-bisallenols. | Deng, Y., et al. 2009. Org Lett. 11: 1205-8. PMID: 19216524
- Synthesis of novel 2, 5-dihydrofuran derivatives and evaluation of their anticancer activity. | Zhang, Y., et al. 2012. Eur J Med Chem. 48: 69-80. PMID: 22182926
- Iron-Catalyzed Cyclization of Alkynols with Diorganyl Diselenides: Synthesis of 2,5-Dihydrofuran, 3,6-Dihydro-2H-pyran, and 2,5-Dihydro-1H-pyrrole Organoselanyl Derivatives. | Casola, KK., et al. 2015. J Org Chem. 80: 7702-12. PMID: 26158240
- Supported Molybdenum Catalysts for the Deoxydehydration of 1,4-Anhydroerythritol into 2,5-Dihydrofuran. | Sandbrink, L., et al. 2017. ChemSusChem. 10: 1375-1379. PMID: 28165202
- Isosarcophytoxide Derivatives with a 2,5-Dihydrofuran Moiety from the Soft Coral Sarcophyton cinereum. | Chao, CH., et al. 2023. Molecules. 28: PMID: 36677699
- Analysis of the proton NMR spectra of 2,5-dihydrofuran, 2,5-dihydrothiophene, and butadiene sulfone | R Lozach, B Braillon - Journal of Magnetic Resonance (1969), 1973 - Elsevier. December 1973,. Journal of Magnetic Resonance (1969). Volume 12, Issue 3,: Pages 244-260.
- Thermal reactions of cyclic ethers at high temperatures. 4. Pyrolysis of 2,5-dihydrofuran behind reflected shocks | Assa Lifshitz, Menashe Bidani, and Shimon Bidani. 1986,. J. Phys. Chem. 90, 22,: 6011–6014.
- Low-pressure selective hydroformylation of 2,3- and 2,5-dihydrofuran with a rhodium catalyst. Unexpected influence of the auxiliary ligand tris(o-t-butylphenyl) phosphite | A. Polo, J. Real, C. Claver, S. Castillón and J. C. Bayón., 1990,. J. Chem. Soc., Chem. Commun. 600-601.
- Focused Microwave-Assisted Synthesis of 2,5-Dihydrofuran Derivatives as Electron Acceptors for Highly Efficient Nonlinear Optical Chromophores† | and S. Liu, M.A. Haller, H. Ma, L.R. Dalton, S.-H. Jang, A.K.-Y. Jen. April, 2003. Advanced Materials. Volume15, Issue7-8: Pages 603-607.
- Rhodium-Catalyzed Diverse Arylation of 2,5-Dihydrofuran: Controllable Divergent Synthesis via Four Pathways | Junhao Xing, Wanjiang Zhu, Bihai Ye, Tao Lu, Tamio Hayashi*, and Xiaowei Dou*. 2020. ACS Catal., 10, 5,: 2958–2963.
- Selective isomerization of 2,5-dihydrofuran to 2,3-dihydrofuran using CO-modified, supported Pd catalysts | JR Monnier, JW Medlin, YJ Kuo - Applied Catalysis A: General, 2000 - Elsevier. 13 March 2000,. Applied Catalysis A: General. Volumes 194–195,: Pages 463-474.
- Can the nonlinearity of hydrogen bonds B…HX be measured precisely? A method from rotational spectroscopy and its application to 2,5-dihydrofuran…HCl | AC Legon, JC Thorn - Chemical physics letters, 1994 - Elsevier. 16 September 1994,. Chemical Physics Letters. Volume 227, Issues 4–5,: Pages 472-479.
- Ring-closing metathesis toward the synthesis of 2,5-dihydrofuran and 2,5-dihydropyrrole skeletons from Baylis–Hillman adducts | JM Kim, KY Lee, S Lee, JN Kim - Tetrahedron letters, 2004 - Elsevier. 22 March 2004,. Tetrahedron Letters. Volume 45, Issue 13,: Pages 2805-2808.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,5-Dihydrofuran, 25 g | sc-225741 | 25 g | $57.00 |