(-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid monohydrate (CAS 68539-16-2)

(−)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid monohydrate is a compound of interest in carbohydrate chemistry and synthetic organic chemistry research. This chemical is primarily used as a key intermediate in the synthesis of ascorbic acid (vitamin C) analogs and derivatives. Its unique structure, containing a di-isopropylidene group and a keto acid functionality, provides strategic opportunities for the selective functionalization and modification of the ascorbic acid scaffold. Researchers utilize (−)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid monohydrate as a precursor in the development of novel vitamin C derivatives with improved stability, bioavailability, and biological activity. Additionally, this compound serves as a valuable tool in mechanistic studies aimed at elucidating the reactivity and transformations of keto acids in organic synthesis. Through its versatile applications in the synthesis of ascorbic acid analogs and mechanistic investigations, (−)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid monohydrate continues to be a pivotal reagent in advancing our understanding of carbohydrate chemistry and facilitating the development of new functional molecules with potential applications in food, pharmaceuticals, and materials science.