Date published: 2026-5-19

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2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (CAS 16297-07-7)

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CAS Number:
16297-07-7
Molecular Weight:
176.07
Molecular Formula:
C6F4N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile is a building block in the synthesis of various organic molecules. It acts as a versatile intermediate in the production of agrochemicals, and materials. 2,3,5,6-Tetrafluoro-4-Pyridinecarbonitrile participates in reactions that involve the formation of carbon-carbon and carbon-heteroatom bonds, contributing to the creation of complex molecular structures. Its mechanism of action involves undergoing substitution and addition reactions, allowing for the introduction of fluorine atoms and cyano groups into the target molecules. Its presence in the synthesis of advanced materials and bioactive compounds highlights its significance in the field of organic chemistry.


2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (CAS 16297-07-7) References

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  8. Functional Regulation and Stability Engineering of Three-Dimensional Covalent Organic Frameworks.  |  Guan, X., et al. 2022. Acc Chem Res. 55: 1912-1927. PMID: 35761434
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  10. Reactions of 4-substituted tetrafluoropyridine derivatives with sulfur nucleophiles: SNAr and annelation processes  |  Mark A. Fox a, Graham Sandford a, Rachel Slater a, Dmitrii S. Yufit b, Judith A.K. Howard b, Antonio Vong c. 2012. Journal of Fluorine Chemistry. 143: 148-154.
  11. Pyrido [3, 2-b][1, 4] oxazine and pyrido [2, 3-b][1, 4] benzoxazine systems from tetrafluoropyridine derivatives  |  Graham Sandford a, Rachel Slater a, Dmitrii S. Yufit b, Judith A.K. Howard b, Antonio Vong c. 2014. Journal of Fluorine Chemistry. 167: 91-95.
  12. Macroscopic covalent organic framework architectures for water remediation  |  Abdul Khayum Mohammed a and Dinesh Shetty *ab. 2021. Environ. Sci.: Water Res. Technol. 7: 1895-1927.
  13. Integrating polyarylether-COFs with TiO2 nanofibers for enhanced visible-light-driven CO2 reduction in artificial photosynthesis  |  Yanxin Gao a, Zunkun Tan a, Rong Yang a, Guocheng Huang a, Jinhong Bi a b. 2022. Applied Surface Science. 605.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile, 1 g

sc-225638
1 g
$188.00