Date published: 2026-2-13

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2,2′-Methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline] (CAS 139021-82-2)

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Alternate Names:
(4R,5S,4′R,5′S)-2,2′-Methylenebis(4,5-diphenyl-2-oxazoline)
CAS Number:
139021-82-2
Molecular Weight:
458.55
Molecular Formula:
C31H26N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,2′-Methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline] serves as a highly versatile building block in organic synthesis, finding widespread applications in research. Its utility extends to the synthesis of diverse compounds, ranging from pharmaceuticals and agrochemicals to materials. This compound proves instrumental in the creation of heterocyclic compounds like oxazoles, thiazoles, and imidazoles. Moreover, it contributes to the synthesis of polymers such as polycarbonates, polyesters, and polyamides. Furthermore, the compound′s involvement extends to the creation of biologically active compounds, including chiral ligands, peptides, and carbohydrates. By acting as an electron donor, it facilitates the transfer of electrons to other molecules during the reaction, thus playing a role in the formation of various synthesized compounds.


2,2′-Methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline] (CAS 139021-82-2) References

  1. C2-symmetric bis(oxazolinato)lanthanide catalysts for enantioselective intramolecular hydroamination/cyclization.  |  Hong, S., et al. 2003. J Am Chem Soc. 125: 14768-83. PMID: 14640652
  2. Synthesis and Structural Analysis of Palladium(II) Complexes Containing Neutral or Anionic C 2-Symmetric Bis(oxazoline) Ligands: Effects of Substituents in the 5-Position.  |  Tsutsumi, K., et al. 2017. ACS Omega. 2: 3886-3900. PMID: 31457695
  3. Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes.  |  Zhang, P., et al. 2020. J Am Chem Soc. 142: 1757-1762. PMID: 31847514

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,2′-Methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline], 1 g

sc-238253
1 g
$312.00