1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (CAS 26853-31-6)

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine, identified by CAS number 70778-75-5, is a phospholipid that plays a critical role in the structure and function of cellular membranes. Comprising two fatty acid chains, palmitic acid at the sn-1 position and oleic acid at the sn-2 position, attached to a glycerol backbone that is further linked to a phosphocholine group, this molecule is a key component of lipid bilayers. In research, 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine is extensively used in the study of membrane dynamics and properties. It serves as a model membrane component for biophysical experiments aimed at understanding membrane fluidity, permeability, and interactions with proteins and other molecules. This phospholipid is particularly valuable in the synthesis of liposomes and other artificial membrane systems, which are used to simulate cellular environments and study the mechanisms of membrane-associated processes. Additionally, it is utilized in the development of delivery systems for studying the efficacy of various compound incorporations into lipid bilayers. By incorporating this phospholipid into experimental setups, researchers can explain the fundamental principles governing cellular membranes and lipid-lipid as well as lipid-protein interactions, which are crucial for the comprehensive understanding of cellular physiology and biochemistry.