Date published: 2026-5-16

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1-Lauroyl-3-chloropropanediol (CAS 20542-96-5)

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Alternate Names:
rac 1-Lauroyl-3-chloropropanediol
Application:
1-Lauroyl-3-chloropropanediol is a glycerol fatty acid ester found in vegetable oils
CAS Number:
20542-96-5
Purity:
98%
Molecular Weight:
292.84
Molecular Formula:
C15H29ClO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Lauroyl-3-chloropropanediol (CAS: 20542-96-5) is a chemically synthesized organic compound that features a lauroyl group (a twelve-carbon fatty acid chain) esterified to glycerol, which has been further modified by the introduction of a chlorine atom at the third carbon. This structural modification is significant as it imparts unique chemical properties to the molecule, particularly affecting its reactivity and interaction with other organic compounds. In research, this compound is often explored for its potential as a building block in organic synthesis and material science due to the reactive chloro group, which can undergo further chemical transformations, such as substitutions and eliminations. The presence of the fatty acid chain also makes it a subject of interest in studies related to lipid analogs and their interactions, providing insights into the assembly, orientation, and dynamics of lipid-like structures in various environments. Additionally, the specific arrangement of functional groups within 1-Lauroyl-3-chloropropanediol allows researchers to investigate the physicochemical properties of chlorinated lipids, including their stability, polarity, and potential to form different molecular assemblies. This kind of research is crucial for advancing our understanding of how modifications at a molecular level can influence the macroscopic properties of materials, particularly those intended for use in specialized industrial applications.


1-Lauroyl-3-chloropropanediol (CAS 20542-96-5) References

  1. Absorption and metabolism of the food contaminant 3-chloro-1,2-propanediol (3-MCPD) and its fatty acid esters by human intestinal Caco-2 cells.  |  Buhrke, T., et al. 2011. Arch Toxicol. 85: 1201-8. PMID: 21327620
  2. Comparison of indirect and direct quantification of esters of monochloropropanediol in vegetable oil.  |  Dubois, M., et al. 2012. J Chromatogr A. 1236: 189-201. PMID: 22444428
  3. Analysis of processing contaminants in edible oils. Part 1. Liquid chromatography-tandem mass spectrometry method for the direct detection of 3-monochloropropanediol monoesters and glycidyl esters.  |  MacMahon, S., et al. 2013. J Agric Food Chem. 61: 4737-47. PMID: 23590632
  4. Occurrence of 3-MCPD and glycidyl esters in edible oils in the United States.  |  MacMahon, S., et al. 2013. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 30: 2081-92. PMID: 24138540
  5. Direct determination of fatty acid esters of 3-chloro-1, 2-propanediol in edible vegetable oils by isotope dilution - ultra high performance liquid chromatography - triple quadrupole mass spectrometry.  |  Li, H., et al. 2015. J Chromatogr A. 1410: 99-109. PMID: 26239698
  6. Extraction and Liquid Chromatography-Tandem Mass Spectrometry Detection of 3-Monochloropropanediol Esters and Glycidyl Esters in Infant Formula.  |  Leigh, JK. and MacMahon, S. 2016. J Agric Food Chem. 64: 9442-9451. PMID: 27960288
  7. Direct determination of 3-chloropropanol esters in edible vegetable oils using high resolution mass spectrometry (HRMS-Orbitrap).  |  Graziani, G., et al. 2017. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 34: 1893-1903. PMID: 28820048
  8. Determination of 3-monochloropropanediol esters and glycidyl esters in fatty matrices by ultra-high performance liquid chromatography-tandem mass spectrometry.  |  Hidalgo-Ruiz, JL., et al. 2021. J Chromatogr A. 1639: 461940. PMID: 33548662
  9. Development of UHPLC/Q-TOF Analysis Method to Screen Glycerin for Direct Detection of Process Contaminants 3-Monochloropropane-1,2-diol Esters (3-MCPDEs) and Glycidyl Esters (GEs).  |  Girard, L., et al. 2021. Molecules. 26: PMID: 33922286
  10. Simultaneous determination of 24 congeners of 2- and 3-monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices.  |  Lee, CC., et al. 2023. J Food Drug Anal. 31: 55-72. PMID: 37224555

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Lauroyl-3-chloropropanediol, 25 mg

sc-213344
25 mg
$330.00