Molecular structure of 1,8-Dihydroxyanthraquinone, CAS Number: 117-10-2
1,8-Dihydroxyanthraquinone (CAS 117-10-2)
Alternate Names:
Chrysazine; Danthron
CAS Number:
117-10-2
Purity:
≥95%
Molecular Weight:
240.21
Molecular Formula:
C14H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
1,8-Dihydroxyanthraquinone, also known as danthrone, a synthetic compound stems from the naturally occurring alkaloid dantrolene. Notably, 1,8-Dihydroxyanthraquinone has been the subject of extensive study in both in vitro and in vivo scenarios. Despite this research, its mechanism of action remains partially shrouded in mystery. However, prevailing beliefs suggest that 1,8-Dihydroxyanthraquinone exerts its effects through the modulation of various ion channels, including calcium, sodium, and potassium channels. These channels play pivotal roles in regulating neuronal excitability, and 1,8-Dihydroxyanthraquinone′s influence on them is thought to underlie its properties.
1,8-Dihydroxyanthraquinone (CAS 117-10-2) References
- Gas chromatographic determination of the laxative 1, 8-dihydroxyanthraquinone in urine and faeces. | Baars, AJ., et al. 1976. J Chromatogr. 120: 217-20. PMID: 1270548
- Reactivity of aromatic amines with triplet 1,8-dihydroxyanthraquinone: a laser flash photolysis study. | Pan, Y., et al. 2007. Spectrochim Acta A Mol Biomol Spectrosc. 66: 63-7. PMID: 16815083
- Intramolecular hydrogen bonding in 1,8-dihydroxyanthraquinone, 1-aminoanthraquinone, and 9-hydroxyphenalenone studied by picosecond time-resolved fluorescence spectroscopy in a supersonic jet. | Müller, C., et al. 2006. J Phys Chem B. 110: 19820-32. PMID: 17020367
- Dissociative photoionization mechanism of 1,8-dihydroxyanthraquinone: an experimental and theoretical study. | Pan, Y., et al. 2008. J Phys Chem A. 112: 10977-84. PMID: 18828582
- 1,8-Dihydroxyanthraquinone anchored on silica gel: synthesis and application as solid phase extractant for lead(II), zinc(II) and cadmium(II) prior to their determination by flame atomic absorption spectrometry. | Goswami, A. and Singh, AK. 2002. Talanta. 58: 669-78. PMID: 18968796
- Danthron (1,8-dihydroxyanthraquinone). | . 2004. Rep Carcinog. 11: III77-8. PMID: 21089845
- Colorimetric and fluorescence sensing of Cu2+ in water using 1,8-dihydroxyanthraquinone-β-cyclodextrin complex with the assistance of ammonia. | Wang, Y., et al. 2012. Talanta. 94: 172-7. PMID: 22608431
- Spectroscopic studies of cutaneous photosensitizing agents--XV. Anthralin and its oxidation product 1,8-dihydroxyanthraquinone. | Dabestani, R., et al. 1990. Photochem Photobiol. 52: 961-71. PMID: 2287637
- Inclusion complex formation of 1,8-dihydroxyanthraquinone with cyclodextrins in aqueous solution and in solid state. | Smulevich, G., et al. 1988. J Pharm Sci. 77: 523-6. PMID: 3171933
- Biotransformation of 1,8-Dihydroxyanthraquinone into Peniphenone under the Fermentation of Aleurodiscus mirabilis. | Mei, R., et al. 2020. ACS Omega. 5: 33380-33386. PMID: 33403300
- Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. | Wu, C., et al. 2022. J Transl Med. 20: 294. PMID: 35765026
- A Chemosensor of 1,8-Dihydroxyanthraquinone PMOs Prepared in a Ternary Deep Eutectic Solvent for the Sensitive Detection of Cu2. | Li, Z. and Han, S. 2022. ACS Omega. 7: 22613-22625. PMID: 35811913
- Influence of 1,8-dihydroxyanthraquinone and loperamide on the paracellular permeability across colonic mucosa. | Verhaeren, EH., et al. 1981. J Pharm Pharmacol. 33: 526-8. PMID: 6115928
- Enhancement of cell proliferation and prostaglandin biosynthesis by 1,8-dihydroxyanthraquinone in the rat large intestine. | Nishikawa, A., et al. 1997. Carcinogenesis. 18: 1259-63. PMID: 9214611
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,8-Dihydroxyanthraquinone, 100 g | sc-223124 | 100 g | $74.00 | |||
1,8-Dihydroxyanthraquinone, 500 g | sc-223124A | 500 g | $144.00 |