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1,2-Dimyristoyl-sn-glycero-3-phosphocholine (CAS 18194-24-6)

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Alternate Names:
1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine
Application:
1,2-Dimyristoyl-sn-glycero-3-phosphocholine is a synthetic phospholipid used to study biological membranes
CAS Number:
18194-24-6
Purity:
≥99%
Molecular Weight:
677.9
Molecular Formula:
C36H72NO8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Dimyristoyl-sn-glycero-3-phosphocholine is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine exhibits characteristics such as remarkable stability, minimal toxicity, and superb solubility. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function. Furthermore, this compound has proven valuable in exploring the interplay between lipids and proteins, elucidating their interactions, and unraveling the impact of lipids on protein structure and functionality.


1,2-Dimyristoyl-sn-glycero-3-phosphocholine (CAS 18194-24-6) References

  1. Effect of free fatty acids on the permeability of 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayer at the main phase transition.  |  Langner, M. and Hui, S. 2000. Biochim Biophys Acta. 1463: 439-47. PMID: 10675520
  2. Quantification of the Raf-C1 interaction with solid-supported bilayers.  |  Eing, A., et al. 2002. Chembiochem. 3: 190-7. PMID: 11921397
  3. Evaluation of the interaction of propranolol with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes: the partitioning model.  |  Cocquyt, J., et al. 2007. Langmuir. 23: 1959-64. PMID: 17279681
  4. Polarization modulation infrared reflection absorption spectroscopy investigations of thin silica films deposited on gold. 2. Structural analysis of a 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayer.  |  Zawisza, I., et al. 2008. Langmuir. 24: 3922-9. PMID: 18327962
  5. Interaction of 5-fluorouracil loaded nanoparticles with 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes used as a cellular membrane model.  |  Lopes, S., et al. 2012. J Phys Chem B. 116: 667-75. PMID: 22148190
  6. Ionic liquid expedites partition of curcumin into solid gel phase but discourages partition into liquid crystalline phase of 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes.  |  El Khoury, ED. and Patra, D. 2013. J Phys Chem B. 117: 9699-708. PMID: 23895644
  7. Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains.  |  Lee, H. 2015. J Mol Graph Model. 60: 162-8. PMID: 26055631
  8. Liquid disordered-liquid ordered phase coexistence in bicelles containing unsaturated lipids and cholesterol.  |  Schmidt, ML. and Davis, JH. 2016. Biochim Biophys Acta. 1858: 619-26. PMID: 26706097
  9. Nanoparticle-Engendered Rupture of Lipid Membranes.  |  Burgess, S., et al. 2018. J Phys Chem Lett. 9: 4872-4877. PMID: 30085675
  10. Modulation of membrane properties by silver nanoparticles probed by curcumin embedded in 1,2-Dimyristoyl-sn-glycero-3-phosphocholine liposomes.  |  Wehbe, N., et al. 2019. Colloids Surf B Biointerfaces. 173: 94-100. PMID: 30273873
  11. Evaluation of EGCG Loading Capacity in DMPC Membranes.  |  Pires, F., et al. 2019. Langmuir. 35: 6771-6781. PMID: 31006246
  12. Effect of pH on the phase behavior of DMPC bilayers.  |  Chowdhury, A., et al. 2021. Biochim Biophys Acta Biomembr. 1863: 183695. PMID: 34273298
  13. Interaction of Dopamine with Zwitterionic DMPC and Anionic DMPS Multilamellar Vesicle Membranes.  |  Sahu, AK. and Mishra, AK. 2021. Langmuir. 37: 13430-13443. PMID: 34732050
  14. Change in Morphology of Dimyristoylphosphatidylcholine/Bile Salt Derivative Bicelle Assemblies with Dodecylmaltoside in the Disk and Ribbon Phases.  |  Leite, WC., et al. 2022. J Phys Chem Lett. 13: 9834-9840. PMID: 36250687
  15. Ca2+-mediated interaction between dextran sulfate and dimyristoyl-sn-glycero-3-phosphocholine surfaces studied by 2H nuclear magnetic resonance.  |  Huster, D. and Arnold, K. 1998. Biophys J. 75: 909-16. PMID: 9675191

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Dimyristoyl-sn-glycero-3-phosphocholine, 100 mg

sc-208728
100 mg
$107.00

1,2-Dimyristoyl-sn-glycero-3-phosphocholine, 1 g

sc-208728A
1 g
$310.00

1,2-Dimyristoyl-sn-glycero-3-phosphocholine, 100 g

sc-208728B
100 g
$13770.00