1,2,3,4,6-Penta-trimethylsilyl Glucopyranose (CAS 19126-99-9)

1,2,3,4,6-Penta-trimethylsilyl glucopyranose, a derivative of glucose, has gained significant attention in carbohydrate chemistry research due to its versatile applications. As a trimethylsilyl (TMS) derivative, it serves as a protective group for the hydroxyl functionalities of glucose, allowing for selective reactions at specific sites within the sugar molecule. This compound finds extensive use in the synthesis and modification of carbohydrates, particularly in the preparation of glycosyl donors and acceptors for oligosaccharide synthesis. Additionally, it is utilized in glycosylation reactions for the assembly of complex carbohydrate structures, as well as in the preparation of carbohydrate-based ligands for studying carbohydrate-protein interactions. Its compatibility with various reaction conditions, coupled with its stability, makes it an invaluable tool in carbohydrate chemistry research. Furthermore, 1,2,3,4,6-Penta-trimethylsilyl glucopyranose has been employed in analytical techniques such as gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) spectroscopy for the structural elucidation and characterization of carbohydrates and glycoconjugates. Overall, this compound plays a crucial role in advancing our understanding of carbohydrate structure-function relationships and in the development of novel carbohydrate-based compounds for various research purposes.