Molecular structure of Zofenopril-d5, CAS Number: 81938-43-4 (unlabeled)
Zofenopril-d5 (CAS 81872-10-8 (unlabeled))
Application:
Zofenopril-d5 Calcium Salt is a compound that is de-esterified into the active inhibitor, Zefenoprilat
CAS Number:
81872-10-8 (unlabeled)
Molecular Weight:
434.58
Molecular Formula:
C22H18D5NO4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Zofenopril-d5 is a deuterated form of Zofenopril. Zofenopril belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. In mass spectrometry and other analytical techniques, deuterated isotopes provide clear markers that distinguish the modified compound from its non-deuterated counterparts and endogenous molecules, improving the sensitivity and specificity of the analyses. Zofenopril-d5 can serve as an internal standard in analytical assays, ensuring the accuracy and reliability of measurements when detecting and quantifying the parent molecule in complex biological matrices. The study of Zofenopril-d5 contributes to the broader understanding of ACE inhibitors′ mechanisms of action.
Zofenopril-d5 (CAS 81872-10-8 (unlabeled)) References
- A review of the angiotensin-converting enzyme inhibitor, zofenopril, in the treatment of cardiovascular diseases. | Borghi, C., et al. 2004. Expert Opin Pharmacother. 5: 1965-77. PMID: 15330734
- The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets. | Lupi, R., et al. 2006. Eur J Endocrinol. 154: 355-61. PMID: 16452552
- Fibroblast growth factor-2 mediates Angiotensin-converting enzyme inhibitor-induced angiogenesis in coronary endothelium. | Donnini, S., et al. 2006. J Pharmacol Exp Ther. 319: 515-22. PMID: 16868034
- Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE). | Cushman, DW., et al. 1989. Br J Clin Pharmacol. 28 Suppl 2: 115S-130S; discussion 130S-131S. PMID: 2557876
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Zofenopril-d5, 1 mg | sc-220408 | 1 mg | $350.00 | |||
Zofenopril-d5, 10 mg | sc-220408A | 10 mg | $2800.00 |