XL-147 derivative 1 (CAS 1349796-36-6)

건강 상태 :

Solid

용해도 :

Soluble in DMSO (12 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), and 30% PEG400/0.5% Tween80/5% propylene glycol (30 mg/ml at 25 °C).

저장 :

Store at -20° C

녹는점 :

248-251° C

밀도 :

~1.39 g/cm³ (Predicted)

굴절률 :

n²⁰_D ~1.67 (Predicted)

IC50 :

PI3Kγ: IC₅₀ = 9 nM; PI3Kα: IC₅₀ = 39 nM; PI3Kδ: IC₅₀ = 43 nM; PI3Kβ: IC₅₀ = 113 nM; DNA-PK: IC₅₀ = 150 nM

PubChem CID :

MDL 번호 :

MFCD18252649

SMILES :

CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC