Telaprevir (CAS 402957-28-2)

건강 상태 :

Solid

용해도 :

Soluble in water (<1 mg/ml at 25 °C), DMSO (136 mg/mL at 25 °C), ethanol (<1 mg/ml at 25 °C), and 30% PEG400/0.5% Tween80/5% propylene glycol (30 mg/ml at 25 °C).

저장 :

Store at -20° C

녹는점 :

221-224° C (dec.)

밀도 :

~1.3 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.58 (Predicted)

IC50 :

HCV NS3-4A serine protease: IC₅₀ = 0.35 µM

PubChem CID :

MDL 번호 :

MFCD11616089

SMILES :

CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5