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SUN2 Antibody (A-10) is a mouse monoclonal IgG2a antibody that detects SUN2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SUN2, also known as sad1/unc-84 protein-like 2, UNC84B, FRIGG, KIAA0668, or RAB5IP, is a 717 amino acid single-pass membrane protein characterized by the presence of one SUN domain, which plays a crucial role in cellular processes. Anti-SUN2 antibody (A-10) targets a protein primarily located in the membranes of the nucleus and endosomes, where SUN2 is involved in the regulation of homotypic endosome fusion, a vital process for maintaining cellular homeostasis and facilitating intracellular transport. The proper functioning of SUN2 is essential, as disruptions in SUN2 activity can lead to various cellular dysfunctions and are implicated in several genetic disorders associated with chromosome 22, including Phelan-McDermid syndrome and neurofibromatosis type 2. Furthermore, the gene encoding SUN2 is situated on chromosome 22, which is notable for housing over 500 genes and being the second smallest human chromosome, highlighting the complexity and significance of genetic interactions in this region. SUN2 monoclonal antibody (A-10) is an invaluable tool for researchers investigating the role of SUN2 in cellular dynamics and its implications in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SUN2 Antibody (A-10) | sc-515330 | 200 µg/ml | $322.00 | |||
SUN2 Antibody (A-10): m-IgG Fc BP-HRP Bundle | sc-538774 | 200 µg Ab; 10 µg BP | $361.00 | |||
SUN2 Antibody (A-10): m-IgGκ BP-HRP Bundle | sc-536444 | 200 µg Ab; 40 µg BP | $361.00 | |||
SUN2 Antibody (A-10): m-IgG2a BP-HRP Bundle | sc-548403 | 200 µg Ab; 10 µg BP | $361.00 |