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SLU7 Antibody (G-3) is a mouse monoclonal IgG1 antibody that detects SLU7 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SLU7 plays a crucial role in the mRNA splicing process, specifically during the second catalytic step where SLU7 is essential for the accurate selection of the adenine-guanine (AG) dinucleotide at the 3′ splice site. This selection is vital for ensuring that the correct exons are joined together, which ultimately influences the production of functional proteins. The proper functioning of SLU7 is particularly important in maintaining the fidelity of gene expression, as errors in splicing can lead to the production of nonfunctional or harmful proteins, contributing to various diseases. SLU7 associates with the spliceosome late in the splicing pathway, and SLU7 depletion in HeLa nuclear extracts has demonstrated a necessity for holding exon 1 in place, facilitating the precise attack on the designated AG. Anti-SLU7 antibody (G-3) is an invaluable tool for researchers studying the intricacies of mRNA splicing and its implications in cellular function and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SLU7 Antibody (G-3) | sc-393664 | 200 µg/ml | $322.00 | |||
SLU7 Antibody (G-3): m-IgG Fc BP-HRP Bundle | sc-538275 | 200 µg Ab; 10 µg BP | $361.00 | |||
SLU7 Antibody (G-3): m-IgGκ BP-HRP Bundle | sc-535853 | 200 µg Ab; 40 µg BP | $361.00 | |||
SLU7 Antibody (G-3): m-IgG1 BP-HRP Bundle | sc-545618 | 200 µg Ab; 20 µg BP | $361.00 | |||
SLU7 (G-3) Neutralizing Peptide | sc-393664 P | 100 µg/0.5 ml | $69.00 | |||
SLU7 Antibody (G-3) X | sc-393664 X | 200 µg/0.1 ml | $322.00 |