Date published: 2026-4-24

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SB 743921 (CAS 940929-33-9)

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Alternate Names:
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl)-4-methylbenzamide hydrochloride
Application:
SB 743921 is a highly potent and active KSP inhibitor
CAS Number:
940929-33-9
Molecular Weight:
553.52
Molecular Formula:
C31H33ClN2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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SB 743921 is a second generation, highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5). SB 743921 is 5-fold more potent against the ATPase activity of KSP than ispinesib. SB 743921 has cytotoxic activity at less than 2 nM in a spectrum of tumor cell lines.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SB 743921, 5 mg

sc-364609
5 mg
$265.00

SB 743921, 10 mg

sc-364609A
10 mg
$666.00