Date published: 2026-4-24

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Pseurotin D (CAS 77409-68-8)

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Application:
Pseurotin D is an inhibitor of IgE production and known for its anticancer and antiparasitic properties
CAS Number:
77409-68-8
Molecular Weight:
431.43
Molecular Formula:
C22H25NO8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pseurotin D is a secondary metabolite belonging to a family of compounds known for their diverse biological activities. This compound is frequently the subject of research in the field of natural products chemistry, where its biosynthetic pathways are explored to understand the mechanisms by which it is produced by fungi. In chemical ecology, Pseurotin D is of interest for its potential role in the interactions between its producing organisms and their environment, including possible defense mechanisms against microbial competition. The compound′s ability to inhibit certain enzymes is also a focal point for biochemical studies, as these properties can shed light on regulatory processes within cells. Additionally, Pseurotin D is used in studies aimed at identifying novel compounds with unique activities, as it serves as a chemical scaffold that can be modified to produce a range of derivatives with varied biological properties.


Pseurotin D (CAS 77409-68-8) References

  1. Antiparasitic and anticancer constituents of the endophytic fungus Aspergillus sp. strain F1544.  |  Martínez-Luis, S., et al. 2012. Nat Prod Commun. 7: 165-8. PMID: 22474943
  2. Cytotoxic compounds from the marine-derived fungus Aspergillus sp. recovered from the sediments of the Brazilian coast.  |  Saraiva, NN., et al. 2015. Nat Prod Res. 29: 1545-50. PMID: 25532964
  3. New cytotoxic furan from the marine sediment-derived fungi Aspergillus niger.  |  Uchoa, PKS., et al. 2017. Nat Prod Res. 31: 2599-2603. PMID: 28135874
  4. Epigenetic modifier induced enhancement of fumiquinazoline C production in Aspergillus fumigatus (GA-L7): an endophytic fungus from Grewia asiatica L.  |  Magotra, A., et al. 2017. AMB Express. 7: 43. PMID: 28213885
  5. Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A.  |  Copmans, D., et al. 2018. ACS Chem Neurosci. 9: 1652-1662. PMID: 29672015
  6. Natural pseurotins and analogs thereof inhibit activation of B-cells and differentiation into the plasma cells.  |  Vašíček, O., et al. 2020. Phytomedicine. 69: 153194. PMID: 32146299
  7. Pseurotin D Inhibits the Activation of Human Lymphocytes.  |  Rubanova, D., et al. 2021. Int J Mol Sci. 22: PMID: 33669259
  8. Pseurotin D Induces Apoptosis through Targeting Redox Sensitive Pathways in Human Lymphoid Leukemia Cells.  |  Mosejová, E., et al. 2021. Antioxidants (Basel). 10: PMID: 34679711
  9. Pseurotin D inhibits delayed type IV hypersensitivity response.  |  Skoroplyas, S., et al. 2022. Chem Biol Interact. 368: 110241. PMID: 36349590
  10. Antiparasitic Activities of Compounds Isolated from Aspergillus fumigatus Strain Discovered in Northcentral Nigeria.  |  Diyaolu, OA., et al. 2023. Antibiotics (Basel). 12: PMID: 36671310

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pseurotin D, 1 mg

sc-396553
1 mg
$148.00