Phosphodiesterase V Inhibitor II MF: C24H25N3O3
MW: 403.5
An inhibitor of phosphodiesterase.

Phosphodiesterase V Inhibitor II

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Application Phosphodiesterase V Inhibitor II is an inhibitor of phosphodiesterase
순도: ≥97%
분자량: 403.5
분자식: C24H25N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Phosphodiesterase V Inhibitor II is a cell-permeable tetrahydro-β-carboline-hydantoin compound. Acts as a potent and highly selective PDE (phosphodiesterase V inhibitor).


References

Daugan, A., et al. 2003. J. Med. Chem. 46, 4533. Daugan, A., et al. 2003. J. Med. Chem. 46, 4525.

Physical State :
Solid
용해도 :
Soluble in DMSO (100 mg/ml), and ethanol.
저장 :
Store at 4° C
녹는점 :
273.14° C (Predicted)
비등점 :
584.75° C at 760 mmHg (Predicted)
밀도 :
1.34 g/cm3 (Predicted)
굴절률 :
n20D 1.69 (Predicted)
IC50 :
PDE V: IC50 = 5 nM (bovine); Intracellular cGMP levels: EC5050 = 1 µM (ANF-treated RSMC); Recombinant PDE I & III: IC50 = > 10 µM (human); PDE II & IV: IC50 = > 10 µM (bovine)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD09037550
SMILES :
CCCCN1C(=O)C2CC3=C(C(N2C1=O)C4=CC=C(C=C4)OC)NC5=CC=CC=C35

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분석증명서

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