Date published: 2025-9-8

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NOS2/iNOS 항체 (C-11): sc-7271

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데이터 시트
  • NOS2/iNOS 항체 C-11 는 마우스 monoclonal IgG1 κ NOS2/iNOS 항체, 635간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • mouse origin의 NOS2에서 C-terminus에 위치한 1126-1144의 아미노산사이에 위치한 항원결정부와 특정결합합니다.
  • NOS2/iNOS 항체 (C-11)는 WB, IP, IF, IHC(P), FCM and ELISA으로 mouse, rat and human유래의 NOS2 (iNOS) 를 감지하는 데에 추천한다.
  • 항-NOS2/iNOS 항체(C-11)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • IF, IHC(P) 와 FCM에 사용가능한 TRITC or Alexa Fluor® 405 결합제품이 있습니다.
  • NOS2/iNOS (C-11): sc-7271무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 는 NOS2/iNOS 항체 (C-11) 가 WB and IHC(P) 에 응용될 때 우선으로 사용하는 이차 항체 검사 시약입니다.이 시약은NOS2/iNOS 항체(C-11) 와 세트로 제공드립니다. (아래의 주문 정보를 참고해 주시길 바랍니다)

빠른 링크

더보기

NOS2 항체(C-11)는 유도성 산화질소 합성효소(iNOS) 또는 NOS2A로도 알려진 산화질소 합성효소 2(NOS2)를 검출하도록 설계된 쥐 단일 클론 IgG1 kappa 경쇄 항체입니다. NOS2 마우스 단일 클론 항체(C-11)는 마우스 NOS2 단백질의 C-말단 부근에 있는 1126-1144번 아미노산 사이의 에피토프 매핑을 표적으로 삼아, 정확한 결합과 신뢰할 수 있는 검출을 보장합니다. NOS2는 면역 반응, 염증, 신경 전달과 같은 다양한 생물학적 과정에 관여하는 다목적 신호 전달 분자인 산화질소(NO)의 합성을 담당하는 중요한 효소입니다. NOS2의 기능은 특히 NOS2가 병원균을 제거하기 위해 다량의 NO를 생성하는 숙주 방어 메커니즘과 염증 경로의 조절에 중요합니다. NOS2 마우스 단일 클론 항체(C-11)는 마우스, 쥐, 인간에서 NOS2를 인식하는 광범위한 종 반응성을 나타내며, 웨스턴 블롯(WB), 면역침전법(IP), 면역형광법(IF), 파라핀 포매 절편을 이용한 면역조직화학(IHCP), 유세포분석법(FCM), 효소결합 면역흡착 분석법(ELISA) 등의 응용 분야에 권장됩니다. 또한 NOS2 단일 클론 항체(C-11)는 비접합 형태와 아가로스, 호스래디시 퍼옥시다아제(HRP), 피코에리트로핀(PE), 플루오레세인 이소티오시아네이트(FITC), 다중 알렉사 플루오르® 접합체 등 다양한 접합 형태로 제공되어 다양한 실험 설정에 유연성을 제공합니다. NOS2 항체(C-11)는 건강과 질병에서 산화질소의 역할을 연구하는 연구자들에게 권장되며, 염증 반응과 잠재적 치료 표적에 대한 이해를 증진하는 데 기여합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

NOS2/iNOS 항체 (C-11) 참고문헌:

  1. 산화 질소의 상피 자가 독성: 백일해의 호흡기 세포 병리에서의 역할.  |  Heiss, LN., et al. 1994. Proc Natl Acad Sci U S A. 91: 267-70. PMID: 7506415
  2. 대식세포에서 NO 합성효소 유도에서 전사인자 IRF-1의 필요성.  |  Kamijo, R., et al. 1994. Science. 263: 1612-5. PMID: 7510419
  3. 산화 질소 합성 효소: 역할, 피해 및 제어.  |  Nathan, C. and Xie, QW. 1994. Cell. 78: 915-8. PMID: 7522969
  4. 산화질소 합성 효소: 구조와 촉매에 관한 측면.  |  Marletta, MA. 1994. Cell. 78: 927-30. PMID: 7522970
  5. 인간 면역결핍 바이러스 1형(HIV-1)에 감염된 단핵구에서 산화질소 합성효소 활성의 조절: HIV 관련 신경 질환에 대한 시사점.  |  Bukrinsky, MI., et al. 1995. J Exp Med. 181: 735-45. PMID: 7530762
  6. 직장에서 NO.  |  Schmidt, HH. and Walter, U. 1994. Cell. 78: 919-25. PMID: 7923361
  7. 산화질소는 생체 내에서 종양 제거 작용을 하는 중요한 매개체입니다.  |  Farias-Eisner, R., et al. 1994. Proc Natl Acad Sci U S A. 91: 9407-11. PMID: 7937779

주문정보

제품명카탈로그 번호 단위가격수량관심품목

NOS2/iNOS 항체 (C-11)

sc-7271
200 µg/ml
$316.00

NOS2/iNOS (C-11): m-IgG Fc BP-HRP 번들

sc-526492
200 µg Ab; 10 µg BP
$354.00

NOS2/iNOS (C-11): m-IgG1 BP-HRP 번들

sc-531865
200 µg Ab; 20 µg BP
$354.00

NOS2/iNOS 항체 (C-11) AC

sc-7271 AC
500 µg/ml, 25% agarose
$416.00

NOS2/iNOS 항체 (C-11) HRP

sc-7271 HRP
200 µg/ml
$316.00

NOS2/iNOS 항체 (C-11) FITC

sc-7271 FITC
200 µg/ml
$330.00

NOS2/iNOS 항체 (C-11) PE

sc-7271 PE
200 µg/ml
$343.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 488

sc-7271 AF488
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 546

sc-7271 AF546
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 594

sc-7271 AF594
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 647

sc-7271 AF647
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 680

sc-7271 AF680
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 790

sc-7271 AF790
200 µg/ml
$357.00

NOS2/iNOS 항체 (C-11) TRITC

sc-7271 TRITC
200 µg/ml
$320.00

NOS2/iNOS 항체 (C-11) Alexa Fluor® 405

sc-7271 AF405
200 µg/ml
$357.00

NOS2/iNOS (C-11) 중화펩타이드

sc-7271 P
100 µg/0.5 ml
$68.00

Nos2内皮功能是什么

Asked by: Season
感谢您的提问。请联系我们的技术支持部门了解更多信息。亚洲技术支持电话(+86) 021-60936350、邮箱asia@scbio.cn、或选择网页上Live Chat中的“中文支持”。 Thank you for your question. Please contact our Technical Service Department for more information. Our Asian Technical Service team is available at (+86) 021-60936350 or asia@scbio.cn or by live chat on our website.
Answered by: Technical Support 12
Date published: 2021-11-25

Is this antibody possible for iNOS detection using IHC-F staning?

Asked by: yueyao
Thank you for your question. Anti-NOS2 Antibody (C-11): sc-7271 is suited for immunohistochemistry in Frozen Tissue Sections and Formalin-Fixed, Paraffin-Embedded Tissue Sections.
Answered by: Tech Support Europe
Date published: 2021-07-30

This NOS2 antibody is a mouse antibody, and it's also recommended for mouse IHC detection, the question is what secondary antibody should I choose for the detection?

Asked by: phhsy
Thank you for your question. You can use any anti-mouse secondary antibody for your IHC on mouse samples. Make sure to use a good blocking reagent or blocking serum before adding antibodies.
Answered by: Tech Service
Date published: 2019-10-25

The host species is mouse, correct?

Asked by: Conner
Yes, this antibody is raised in a mouse.
Answered by: Technical Support
Date published: 2018-12-21

Hi, can this antibody be use on rat's retina in iNOS detection using IHC staning?

Asked by: Fatt
Thank you for your question. Yes, this antibody is suitable for detection of iNOS, also designated NOS2, in rat tissues. We are aware of publications citing use of this antibody in retina tissue specifically. For example, PMID's: 21712024 and 20621070.
Answered by: Technical Support
Date published: 2023-08-11

How specific is NOS2 (c-11) for Rat. I would like to try it for iNOS detection in rat brain tissue. Please provide me any information related to this. I will highly appreciate your quickest response.

Asked by: Golam Mustafa
Thank you for your question.This antibody is very good for use on rat samples, we have many publications on rat samples, including rat neuronal tissue. Please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com if you have any further questions.
Answered by: Tech Service
Date published: 2017-06-28

Welcher Clon verbirgt sich hinter dem Antikörper NOS2 (C-11) (Bestell-Nr.: sc-7271 AF647)?

Asked by: Ahornblatt5
Vielen Dank für Ihre Anfrage und Ihr Interesse an diesem Produkt. Der NOS2 Antikörper (C-11): sc-7271 ist ein hauseigenes Produkt. Unsere interne Bezeichnung für diesen Klon ist C-11 wie im Produktnamen innerhalb der Klammern angegeben. Für weitere Informationen wenden Sie sich bitte an unseren Technischen Service in unserem Europäischen Supportbüro in Heidelberg. Sie erreichen uns telefonisch unter 06221 4503 0, per email an: europe@scbt.com oder per Live-Chat auf unserer Webseite www.scbt.com Wir freuen uns Ihnen weiterzuhelfen.
Answered by: Technical Support Europe
Date published: 2017-05-16

Dose it work well in rat brain tissue for IF?

Asked by: soahmen
Thank you for your question. Yes, this antibody should be fine for rat brain samples on IF applications. It is a very strong antibody that has been published previously in rat brain samples. If you have any further questions, please contact our Asia Technical Service team. You can reach them by phone at (86 21) 6093-6350, by email at: asia@scbio.cn or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-02-23
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Rated 5 out of 5 by from ExcellentTo be honest, everyone knows that Santa's antibody didn't work sometimes. In my IFC experiment, all cells turned red, and although the control group showed a lower signal than the inflammation group, I was still concerned about whether it was non-specific binding. However, after introducing an LPS-treated positive control group, the results became highly specific. This made me realize that the antibody is actually useful. It seems that the inflammation inducer I used might have behaved a bit unusually, but the antibody itself performs well.
Date published: 2025-06-06
Rated 5 out of 5 by from GoodGreat antibody for WB, works in mouse RAW 264.7 cells
Date published: 2025-03-18
Rated 1 out of 5 by from Did not workDid not work. It just did not work/do what it was supposed to do
Date published: 2025-02-26
Rated 5 out of 5 by from Great features for western blotThe antibody can give a nice clean band. It is a good antibody.
Date published: 2024-07-03
Rated 5 out of 5 by from Expression for oxidative stressNOS2 expression showing presence of inflammation at the defect site in a osteoporotic infectious hip fracture study
Date published: 2024-06-12
Rated 5 out of 5 by from The antibody was greatFew months ago, we determined the iNOS level in colon tissues of mice. The band was clear and precise.
Date published: 2024-01-02
Rated 5 out of 5 by from opinions about antibodiesvery good antibodies, high detection, work very well with the highest dilution declared on the leaflet
Date published: 2023-04-16
Rated 5 out of 5 by from Clean and specific to NOS2Clean and specific antibody. Tested on western blot analysis
Date published: 2023-01-25
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NOS2/iNOS 항체 (C-11) is rated 4.1 out of 5 by 69.
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