Date published: 2026-6-3

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MBP Antibody (1.B.645): sc-71546

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Datasheets
  • MBP Antibody (1.B.645) is a mouse monoclonal IgG2b, cited in 18 publications, provided at 100 µg/ml
  • raised against amino acids 130-136 of MBP of human origin
  • recommended for detection of MBP (human 21.5 kDa and 18.5 kDa molecular forms) of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • See MBP (F-6): sc-271524 for MBP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MBP Antibody (1.B.645). This work is in progress.
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MBP Antibody (1.B.645) is a mouse monoclonal IgG2b light chain antibody that detects myelin basic protein (MBP) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. MBP is a crucial component of the myelin sheath in the central nervous system, playing a vital role in the insulation of axons, which is essential for the rapid transmission of electrical signals between neurons. The structure of MBP consists of a highly charged, flexible protein that interacts with lipids in the myelin membrane, contributing to the stability and integrity of the myelin sheath. Disruptions in MBP function or structure can lead to demyelinating diseases, such as multiple sclerosis, highlighting the significance of MBP in maintaining neuronal health. Anti-MBP antibody (1.B.645) serves as an invaluable tool for researchers studying myelination processes, neuronal signaling, and the pathophysiology of demyelinating disorders, providing insights into the molecular mechanisms underlying these critical biological functions.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MBP Antibody (1.B.645)

sc-71546
100 µg/ml
$322.00

What is the recommended storage condition for MBP (1.B.645): sc-71546?

Asked by: Randy McDonald
Thank you for your question. We recommend storing the antibody at 4° C.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from beautiful staining in tracts of fibersThe antibody produced a beautiful staining in tracts of fibers, i.e. the type of staining expected for MBP.
Date published: 2017-02-13
Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2013-03-14
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MBP Antibody (1.B.645) is rated 4.0 out of 5 by 2.
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