KID Antibody (E-3): sc-390533

KID Antibody (E-3) is a mouse monoclonal IgG1 antibody that detects KID (kinesin-like DNA-binding protein) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). KID plays a crucial role in the regulation of spindle formation and chromosome movement during both mitosis and meiosis, binding to microtubules and interacting with DNA. KID′s unique structure features a kinesin-like motor domain in its N-terminal half, essential for movement along microtubules, while the C-terminal region contains a helix-hairpin-helix DNA-binding domain facilitating chromosomal DNA interaction. This structural arrangement ensures precise chromosomal alignment and segregation during cell division, processes critical for maintaining genomic stability. Anti-KID antibody (E-3) serves as an invaluable tool for researchers studying cell division and related cellular processes, providing insights into chromosomal dynamics and their implications in various diseases.

The preferred KID antibody is KID Antibody (B-9): sc-390640.