human origin의 Espin에서 에 가까운 645-767 아미노산을 항원으로 사용하였습니다.
안티-Espin 항체 (E-7)는 WB, IP, IF and ELISA으로 mouse, rat and human유래의 Espin 를 감지하는 데에 추천한다.; 이외에, canine and porcine등 species와 반응할수 있습니다
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-Espin 항체 (E-7)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Espin Antibody (E-7) is a high quality monoclonal Espin antibody (also designated Espin antibody) suitable for the detection of the Espin protein of mouse, rat and human origin. Espin Antibody (E-7) is available as both the non-conjugated anti-Espin antibody form, as well as multiple conjugated forms of anti-Espin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Espin (ESPN), also known as autosomal recessive deafness type 36 protein (DFNB36), is an 854 amino acid cytoplasmic protein that contains nine ANK repeats and one WH2 domain. The WH2 domain of Espin binds actin monomers and mediates the assembly of the actin bundle. This interaction plays a major role in the moderation of the organization, dynamics and signaling capacities of the actin filament-rich specializations that regulate sensory transduction in various sensory cells. Defects in Espin are the cause of non-syndromic sensorineural deafness autosomal recessive type 36 (DFNB36), a sensorineural hearing loss caused by damage to the neural receptors of the inner ear, the nerve pathways to the brain or the region of the brain responsible for sound. In humans, Espin is expressed as two isoforms produced by alternative splicing and has been found to interact with IRSp53 and Profilin-2. In rodents, four major isoforms ranging from approximately 110 to 25 kDa have been identified with additional splice variants possible.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences