CUDC-101 (CAS 1012054-59-9)

모습 :

Powder

건강 상태 :

Solid

용해도 :

Soluble in DMSO (20 mg/mL at 25 °C), water (<1 mg/mL at 25 °C), ethanol (<1 mg/mL at 25 °C), and 15% captisol (30 mg/mL at 25 °C).

저장 :

Store at -20° C

밀도 :

~1.3 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.64 (Predicted)

IC50 :

mTORC2: IC₅₀ = 2.4 nM (human); HDAC1: IC₅₀ = 4.5 nM (human); HDAC6: IC₅₀ = 5.1 nM (human); HDAC3: IC₅₀ = 9.1 nM (human); HDAC5: IC₅₀ = 11.4 nM (human)

pK 값 :

pK_a: 9.47 (Predicted), pK_b: 5.49 (Predicted)

WGK 독일 :

3

PubChem CID :

MDL 번호 :

MFCD15528940

SMILES :

COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO