human origin의 BMP-2/4에서 내부에 위치한 300-350 아미노산을 항원으로 사용하였습니다.
안티-BMP-2/4 항체 (H-1)는 WB, IP, IF and ELISA으로 mouse, rat and human유래의 precursor and mature BMP-2 and BMP-4 를 감지하는 데에 추천한다.; 이외에, canine, bovine and porcine등 species와 반응할수 있습니다
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-BMP-2/4 항체 (H-1)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for BMP-2/4 Antibody (H-1) for WB applications. These reagents are now offered in bundles with BMP-2/4 Antibody (H-1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
BMP-2/4 Antibody (H-1) is a high quality monoclonal BMP-2/4 antibody (also designated BMP2/4 antibody, or BMP2A/B antibody) suitable for the detection of the BMP-2/4 protein of mouse, rat and human origin. BMP-2/4 Antibody (H-1) is available as both the non-conjugated anti-BMP-2/4 antibody form, as well as multiple conjugated forms of anti-BMP-2/4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Tumor growth factor, or TGFβ, is the prototypic member of a family of secreted proteins that regulate cellular proliferation and differentiation. Related proteins include the activins and the bone morphogenic proteins or BMPs. Like TGFβ, the BMPs signal through a heteromeric receptor complex (TGFβ R) composed of type I (TGFβ RI) and type II (TGFβ RII) receptors. Both the type I and the type II receptors contain an intrinsic serine/threonine kinase activity. Although signaling downstream of the TGF β R is poorly understood, several proteins have been implicated. Six TGFβ/BMP effector proteins, designated Smad1-6, may function as tumor suppressors. Smad proteins have been suggested to be transcription factors, acting similarly to the Stat family which associates directly with activated receptors and then translocates to the nucleus. Evidence supporting this assertion is drawn from the observation that Smad3 physically associates with the TGFβ R complex and that Smad1 is translocated to the nucleus 30-60 minutes after the addition of BMP-4.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences