Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Aldose Reductase (also designated ALR2) is member of the monomeric NADPH-dependent aldoketoreductase family. Aldose Reductase catalyzes the reduction of various aldehydes and has been implicated in the development of diabetic complications by catalyzing the reduction of the aldehyde form of glucose, to the corresponding sugar alcohol, sorbitol. This pathway plays a minor role in glucose metabolism in most tissues, however in diabetic hyperglycemia, cells undergoing insulin-independent uptake of glucose accumulate significant quantities of sorbitol. The resulting hyperosmotic stress to cells may be a cause of diabetic complications such as neuropathy, retinopathy, and cataracts. Aldose Reductase is very similar to human aldehyde reductase (designated ALR1), bovine prostaglandin F synthase and to the European common frog protein, rho-crystallin.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What application is the blocking peptide sc-373953 P appropriate for?
Asked by: DefinitelyNotMatt
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here:
Rated 5 out of
Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human esophagus tissue. -SCBT QC
Date published: 2015-03-11
Rated 5 out of
Nice Western Blot data of Aldose ReductaseNice Western Blot data of Aldose Reductase expression in Caki-1 whole cell lysate. -SCBT QC