Date published: 2025-10-15

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Testicular Receptor 2 (TR2, also known as NR2C1) is a nuclear receptor that can act as a transcription factor. There are no known direct chemical activators for TR2. However, several compounds may influence the function of TR2 indirectly through related pathways or cellular processes. TR2 Activators represent a class of chemicals that can influence the function of TR2. These compounds can indirectly influence the function of TR2 through their effects on related cellular pathways.

Chemicals such as 9-cis Retinoic Acid, All-trans Retinoic Acid, Dexamethasone, Estradiol, Progesterone, Testosterone, Diethylstilbestrol, Tamoxifen, T3, T4, Calcitriol, and Pioglitazone can potentially influence TR2 function through their effects on TR2-related pathways. The effects of these chemicals on TR2 function are context-dependent and may vary based on the cellular environment and other biochemical parameters.

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