TGFβ2 Antibody (B-10): sc-374658
- TGFβ2 Antibody (B-10) is a mouse monoclonal IgG3 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 343-377 at the C-terminus of TGFβ2 of human origin
- recommended for detection of mature and precursor forms of TGFβ2 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See TGFβ2 (H-6): sc-374659 for TGFβ2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for TGFβ2 Antibody (B-10) for WB applications. This reagent is now offered in a bundle with TGFβ2 Antibody (B-10) (see ordering information below).
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TGFβ2 Antibody (B-10) is a mouse monoclonal IgG3 kappa light chain antibody that detects TGFβ2 from mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TGFβ2 antibody (B-10) is available in non-conjugated form. Transforming growth factor β2 (TGFβ2) plays a crucial role in various biological processes, including cell proliferation, differentiation, and immune regulation, making TGFβ2 essential for maintaining tissue homeostasis and mediating responses to injury. TGFβ2 is primarily secreted by various cell types, including fibroblasts and epithelial cells, and is found in the extracellular matrix, where TGFβ2 influences cellular behavior and communication. Proper functioning of TGFβ2 is vital, as dysregulation can lead to pathological conditions such as fibrosis, cancer, and autoimmune diseases. TGFβ2 is synthesized as a precursor protein that undergoes cleavage to produce a biologically active form, which requires dimerization for activity. Mature TGFβ2 shares significant structural similarities with TGFβ1 and TGFβ3, highlighting the evolutionary conservation of function across species. With an ability to mediate critical signaling pathways, TGFβ2 is a key player in developmental processes and tissue repair, making TGFβ2 (B-10) antibody an invaluable tool for researchers studying these complex biological mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TGFβ2 Antibody (B-10) | sc-374658 | 200 µg/ml | $322.00 | |||
TGFβ2 Antibody (B-10): m-IgG3 BP-HRP Bundle | sc-550582 | 200 µg Ab; 40 µg BP | $361.00 | |||
TGFβ2 (B-10) Neutralizing Peptide | sc-374658 P | 100 µg/0.5 ml | $69.00 |