REM2 Antibody (D-12): sc-514898
- REM2 Antibody (D-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 309-326 near the C-terminus of REM2 of human origin
- recommended for detection of REM2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for REM2 Antibody (D-12) for WB applications. These reagents are now offered in bundles with REM2 Antibody (D-12) (see ordering information below).
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REM2 Antibody (D-12) is a mouse monoclonal IgG1 antibody that detects REM2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). REM2, a 340 amino acid cell membrane protein, functions as a GTPase and is a member of the RGK family within the small GTPase superfamily, playing a crucial role in cellular signaling pathways. REM2 acts as a suppressor of the p53 pathway, which is vital for regulating the cell cycle and preventing tumor formation, thereby contributing to cellular proliferation and survival. REM2 mediates the fibroblastic growth factor 2 (FGF-2) signaling pathway, which is essential for maintaining the proliferation of human embryonic stem cells, highlighting REM2′s importance in developmental biology and regenerative medicine. REM2 is predominantly expressed in the kidney and brain, and REM2′s gene is located on human chromosome 14q11.2, a region that also harbors genes associated with significant health conditions, including Alzheimer′s disease and α1-antitrypsin deficiency. Anti-REM2 antibody (D-12) is an invaluable tool for researchers investigating REM2′s roles in various biological processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
REM2 Antibody (D-12) | sc-514898 | 200 µg/ml | $322.00 | |||
REM2 Antibody (D-12): m-IgG Fc BP-HRP Bundle | sc-541007 | 200 µg Ab; 10 µg BP | $361.00 | |||
REM2 Antibody (D-12): m-IgG1 BP-HRP Bundle | sc-542525 | 200 µg Ab; 20 µg BP | $361.00 | |||
REM2 (D-12) Neutralizing Peptide | sc-514898 P | 100 µg/0.5 ml | $69.00 |