Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Rab 25 Antibody (3F12F3) is a high quality monoclonal Rab 25 antibody (also designated RAB25 antibody or CATX8 antibody) suitable for the detection of the Rab 25 protein of mouse, rat and human origin. Rab 25 Antibody (3F12F3) is available as both the non-conjugated anti-Rab 25 antibody form, as well as multiple conjugated forms of anti-Rab 25 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 25, also known as CATX-8 or Rab 11c, is a member of the Rab family of proteins that is exclusively expressed in epithelial cells and participates in apical vesicle trafficking. Rab 25 is overexpressed in ovarian and breast cancer cells and has been associated with metastasis and tumor aggressiveness. The forced expression of Rab 25 in ovarian and breast cancer cells increases cell proliferation in vivo.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can Rab 25 (3F12F3): sc-65978 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Thank you for your question. Yes, Rab 25 (3F12F3): sc-65978 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: