PRL-3 抑制剤 (CAS 893449-38-2)
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別名:
1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine
アプリケーション：
PRL-3 Inhibitor is a cell permeable benzylidene rhodanine compound
CAS 番号:
893449-38-2
Purity:
≥98%
Molecular Weight:
485.21
Molecular Formula:
C17H11Br2NO2S2
補足情報:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
PRL-3 Inhibitor is a cell-permeable benzylidene rhodanine compound that potently inhibits PRL-3 (hPRL-3), a member of the regenerating liver family tyrosine phosphatases. PRL-3 Inhibitor has been shown to reduce the invasiveness of murine melanoma B16F10 cells.
参考文献
1. Ahn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16: 2996-2999. PMID: 16530413
Physical State
:
Solid
Solubility
:
Soluble in DMSO (5 mg/ml). Slight warming may be necessary for complete solubilization.
保存方法
:
Store at -20° C
Melting Point
:
268.90° C (Predicted)
Boiling Point
:
620.54° C (Predicted)
Density
:
1.86 g/cm3 (Predicted)
Refractive Index
:
n20D 1.77 (Predicted)
IC50
:
hPRL-3 : IC50 = 900 nM
pK Values
:
pKa: 7.11 (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
Transport
:
UN 3077, Class 9, Packing group III
PubChem CID
:
SMILES
:
C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)/C=C\\3/C(=O)NC(=S)S3)Br
Download SDS (MSDS)
分析表
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