PPP2R5E Antibody (A-11): sc-376176
- PPP2R5E Antibody (A-11) is a mouse monoclonal IgG2b κ PPP2R5E antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 183-264 mapping within an internal region of PPP2R5E of human origin
- PPP2R5E Antibody (A-11) is recommended for detection of PPP2R5E of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- Anti-PPP2R5E Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for PPP2R5E Antibody (A-11) for WB and IHC(P) applications. This reagent is now offered in a bundle with PPP2R5E Antibody (A-11) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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PPP2R5E Antibody (A-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects PPP2R5E in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-PPP2R5E antibody (A-11) is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. PPP2R5E, also known as protein phosphatase 2, regulatory subunit B′, epsilon isoform, consists of 467 amino acids and is primarily located in the cytoplasm, where PPP2R5E plays a crucial role in the regulation of protein phosphatase activity. As a regulatory subunit of the protein phosphatase holoenzyme, PPP2R5E is essential for modulating the catalytic activity and substrate specificity of the complex, which is vital for maintaining cellular functions such as division, homeostasis, and apoptosis. Proper localization of PPP2R5E within subcellular compartments is important for ensuring that the protein phosphatase complex can effectively interact with its substrates, thereby influencing various signaling pathways and cellular responses.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PPP2R5E Antibody (A-11) References:
- Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit. | Dozier, C., et al. 2004. Biol Cell. 96: 509-17. PMID: 15380617
- Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription. | Ammosova, T., et al. 2005. Retrovirology. 2: 47. PMID: 16048649
- The tumor suppressor PP2A Abeta regulates the RalA GTPase. | Sablina, AA., et al. 2007. Cell. 129: 969-82. PMID: 17540176
- A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. | Goudreault, M., et al. 2009. Mol Cell Proteomics. 8: 157-71. PMID: 18782753
- Identification of a new family of protein phosphatase 2A regulatory subunits. | McCright, B. and Virshup, DM. 1995. J Biol Chem. 270: 26123-8. PMID: 7592815
- The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. | McCright, B., et al. 1996. J Biol Chem. 271: 22081-9. PMID: 8703017
- Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12. | McCright, B., et al. 1996. Genomics. 36: 168-70. PMID: 8812429
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPP2R5E Antibody (A-11) | sc-376176 | 200 µg/ml | $322.00 | |||
PPP2R5E Antibody (A-11): m-IgGκ BP-HRP Bundle | sc-522863 | 200 µg Ab, 40 µg BP | $361.00 | |||
PPP2R5E Antibody (A-11) AC | sc-376176 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PPP2R5E Antibody (A-11) HRP | sc-376176 HRP | 200 µg/ml | $322.00 | |||
PPP2R5E Antibody (A-11) FITC | sc-376176 FITC | 200 µg/ml | $336.00 | |||
PPP2R5E Antibody (A-11) PE | sc-376176 PE | 200 µg/ml | $349.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 488 | sc-376176 AF488 | 200 µg/ml | $364.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 546 | sc-376176 AF546 | 200 µg/ml | $364.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 594 | sc-376176 AF594 | 200 µg/ml | $364.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 647 | sc-376176 AF647 | 200 µg/ml | $364.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 680 | sc-376176 AF680 | 200 µg/ml | $364.00 | |||
PPP2R5E Antibody (A-11) Alexa Fluor® 790 | sc-376176 AF790 | 200 µg/ml | $364.00 |