NAB1 Antibody (B-5): sc-137116
- NAB1 Antibody (B-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 281-486 mapping at the C-terminus of NAB1 of human origin
- recommended for detection of NAB1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NAB1 Antibody (B-5) for WB applications. These reagents are now offered in bundles with NAB1 Antibody (B-5) (see ordering information below).
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NAB1 Antibody (B-5) is a mouse monoclonal IgG2b antibody that detects NAB1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NAB1 (B-5) antibody specifically targets NAB1, which plays a crucial role in transcriptional regulation by acting as a corepressor of the transcription factor Egr1/NGFI-A. NAB1 is primarily located in the nucleus, where NAB1 is essential for modulating gene expression related to critical cellular processes such as cell division, differentiation, and apoptosis. The nuclear localization of NAB1 allows for direct interaction with DNA-bound transcription factors, thereby influencing the transcriptional landscape of the cell. Furthermore, NAB1′s ability to bind to Egr1/NGFI-A is mediated by its amino-terminal NAB-conserved domain 1 (NCB1), which is vital for its repressive function. Understanding the function and localization of NAB1 is important for elucidating NAB1′s role in various biological processes and potential implications in diseases where transcriptional dysregulation occurs.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAB1 Antibody (B-5) | sc-137116 | 200 µg/ml | $322.00 | |||
NAB1 Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-537402 | 200 µg Ab; 10 µg BP | $361.00 | |||
NAB1 Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-534657 | 200 µg Ab; 40 µg BP | $361.00 | |||
NAB1 Antibody (B-5): m-IgG2b BP-HRP Bundle | sc-549867 | 200 µg Ab; 10 µg BP | $361.00 |