Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
N-type Ca++ CP α1B Antibody (A-2) is a high quality monoclonal N-type Ca++ CP alpha 1B antibody (also designated N-type Ca++ CP α1B antibody) suitable for the detection of the N-type Ca++ CP alpha 1B protein of mouse, rat and human origin. N-type Ca++ CP α1B Antibody (A-2) is available as the non-conjugated anti-N-type Ca++ CP alpha 1B antibody. N-type calcium channels are localized in high density presynaptic nerve terminals and are crucial elements in neuronal excitation-secretion coupling. Peripherally distributed N-type Ca++ channel plays a key role in cardiovascular regulation through autonomic nervous system. The high-voltage activated Ca++ channels that have been characterized biochemically are complexes of a pore-forming a-1 subunit; a transmembrane, disulfide-linked complex of a-2 and d subunits; an intracellular b subunit; and in some cases, a transmembrane g subunit. The a-1 subunit conducts N-type Ca++ currents, which initiate rapid synaptic transmission. In addition to mediating Ca++ entry to initiate transmitter release, N-type Ca++ channels are thought to interact directly with proteins of the synaptic vesicle docking and fusion machinery. The synaptic protein interaction sites in the intracellular loop II-III of subunit a-1B of N-type Ca++ channels bind to syntaxin, SNAP-25 and synaptotagmin.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.