Mosxe Antibody (R38.1): sc-53372
- Mosxe Antibody (R38.1) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against maltose binding protein-Xenopus Mos fusion protein
- recommended for detection of Mos p39 of x origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Mosxe Antibody (R38.1). This work is in progress.
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Mosxe Antibody (R38.1) is a mouse monoclonal IgG2b kappa light chain antibody that detects the Mosxe protein of x origin by western blotting (WB). Mosxe, a cellular homolog of the v-Mos oncogene derived from the Moloney strain murine sarcoma virus, plays a crucial role in the regulation of meiosis in vertebrate oocytes. Mosxe protein is primarily located in germ cells, where expression levels are relatively high compared to somatic cells, highlighting its importance in reproductive biology. Mosxe functions as a serine/threonine kinase, and activity is essential for the stabilization and activation of the maturation promoting factor (MPF) complex during oocyte maturation. This process is vital for proper cell division and development, ensuring oocytes are ready for fertilization. Furthermore, when ectopically expressed during the G1 phase of the cell cycle, Mosxe can induce oncogenic transformation of somatic cells, demonstrating potential role in cancer biology. Anti-Mosxe antibody (R38.1) is an invaluable tool for researchers studying the intricate mechanisms of meiosis and implications of Mosxe in oncogenesis, providing insights into both normal and pathological cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mosxe Antibody (R38.1) | sc-53372 | 200 µg/ml | $322.00 |