LY2784544 CAS: 1229236-86-5
MF: C23H25ClFN7O
MW: 469.94
A selective inhibitor of JAK2 mutant V617F.

LY2784544 (CAS 1229236-86-5)

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別名: 3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine
アプリケーション: LY2784544 is a selective inhibitor of JAK2 mutant V617F
CAS 番号: 1229236-86-5
Molecular Weight: 469.94
Molecular Formula: C23H25ClFN7O
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* Refer to Certificate of Analysis for lot specific data (including water content).
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LY2784544 is identified as being highly selective inhibitor of JAK2 mutant V617F and has advanced into human clinical trials for the treatment of several myeloproliferative disorders.

Physical State :
Solid
Solubility :
Soluble in DMSO (≥ 91 mg/ml), water (< 1.2 mg/ml), and ethanol (≥ 8.8 mg/ml).
保存方法 :
Store at -20° C
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.70 (Predicted)
pK Values :
pKa: 4.38 (Predicted)
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
PubChem CID :
SMILES :
CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F

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