L-(-)-threo-3-Hydroxyaspartic acid (CAS 7298-99-9)
別名:
L-threo-β-Hydroxyaspartic acid
アプリケーション：
L-(−)-threo-3-Hydroxyaspartic acid is a potent & competitive EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
CAS 番号:
7298-99-9
Purity:
≥97%
Molecular Weight:
149.1
Molecular Formula:
C4H7NO5
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
L-(-)-threo-3-Hydroxyaspartic acid is a potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor.
参考文献
Johnston et al (1980) Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate. J.Neurochem. 34 241. McBean and Roberts (1985) Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J.Neurochem. 44 247. Nakamura et al (1993) (2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate. Neuropharmacolgy 32 833.
Physical State
:
Solid
Solubility
:
Soluble to 100 mM in 1eq. NaOH
保存方法
:
Store at -20° C
Melting Point
:
257.34° C (Predicted)
Boiling Point
:
368.6° C at 760 mmHg (Predicted)
Density
:
1.74
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
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分析表
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