IL-6Rα Antibody (2B2.3): sc-71366
- IL-6Rα Antibody (2B2.3) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against CHO cells transfected with IL-6Rα of human origin
- recommended for detection of of origin by FCM
- See IL-6Rα (H-7): sc-373708 for IL-6Rα antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-6Rα Antibody (2B2.3). This work is in progress.
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IL-6Rα Antibody (2B2.3) is a mouse monoclonal IgG1 antibody that detects IL-6Rα in various species by flow cytometry (FCM). IL-6Rα, also known as gp80, plays a crucial role in the immune response by serving as the primary receptor for interleukin-6 (IL-6), a key cytokine involved in inflammation and immune regulation. IL-6Rα forms a signaling complex with gp130, which is essential for activating intracellular pathways that mediate cellular responses to IL-6. This receptor complex facilitates signal transmission that promotes inflammation and influences processes such as hematopoiesis and the acute phase response. A soluble form of IL-6Rα, generated through proteolytic cleavage, can enhance IL-6 signaling in a paracrine manner, further underscoring IL-6Rα′s significance in both normal physiology and pathological conditions. Anti-IL-6Rα antibody (2B2.3) serves as an invaluable tool for researchers studying IL-6 signaling in various diseases, including autoimmune disorders and cancers, advancing our understanding of immune system dynamics.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-6Rα Antibody (2B2.3) | sc-71366 | 100 µg/ml | $322.00 |