GRWD1 Antibody (B-7): sc-514125

GRWD1 Antibody (B-7) is a mouse monoclonal IgG2b antibody that detects GRWD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GRWD1, also known as glutamate-rich WD repeat-containing protein 1 or WDR28, is a 446 amino acid protein characterized by five WD repeats and is primarily localized in the nucleus. GRWD1 (B-7) antibody targets a crucial component of the 50S and 80S preribosomal complexes, playing a significant role in ribosome biogenesis, which is essential for protein synthesis in cells. Proper functioning of GRWD1 is vital, as ribosome biogenesis is a highly regulated process that impacts cell growth and proliferation. Dysregulation of this process can lead to various diseases, including cancer and genetic disorders. The gene encoding GRWD1 is located on human chromosome 19q13.33, a region known for its high gene density and association with several genetic conditions, highlighting the importance of GRWD1 in both normal cellular function and disease states. Anti-GRWD1 antibody (B-7) provides a reliable tool for researchers investigating the role of GRWD1 in various biological processes and diseases.

The preferred GRWD1 antibody is GRWD1 Antibody (D-1): sc-514042.