FeLV p27 Antibody (PF12J-10A): sc-65623

FeLV p27 Antibody (PF12J-10A) is a mouse monoclonal IgG antibody that detects p27 protein of feline leukemia virus (FeLV) origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). FeLV p27 (PF12J-10A) antibody is available in a non-conjugated form, providing researchers with a versatile tool for studying this critical viral protein. p27 protein serves as the major core protein of FeLV, playing a vital role in the virus′s structure and function. p27 protein′s importance lies in encapsulating the viral RNA genome, which is essential for virus replication and infection process. Understanding p27 structure is crucial, as p27 aids in virus identification and provides insights into viral assembly mechanisms and potential targeted therapies. Feline leukemia virus, a retrovirus primarily affecting cats, is transmitted through various routes, including saliva and nasal secretions, and can lead to severe immunosuppression, affecting approximately 30% of infected cats. p27 presence in infected tissues can serve as a biomarker for diagnosing FeLV, making FeLV p27 (PF12J-10A) monoclonal antibody an invaluable resource for veterinary research and diagnostics.

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FeLV p27 Antibody (PF12J-10A) References:

1. Infections of feline leukemia virus and feline immunodeficiency virus.  |  Miyazawa, T. 2002. Front Biosci. 7: d504-18. PMID: 11815291
2. Host range and receptor binding properties of vectors bearing feline leukemia virus subgroup B envelopes can be modulated by envelope sequences outside of the receptor binding domain.  |  Faix, PH., et al. 2002. J Virol. 76: 12369-75. PMID: 12414980
3. Feline leukemia virus threatens endangered panthers.  |  Nolen, RS. 2004. J Am Vet Med Assoc. 224: 1721-2. PMID: 15198250
4. Prevalence of canine distemper virus, feline immunodeficiency virus and feline leukemia virus in captive African lions (Panthera leo) in Japan.  |  Endo, Y., et al. 2004. J Vet Med Sci. 66: 1587-9. PMID: 15644613
5. Re-examination of feline leukemia virus: host relationships using real-time PCR.  |  Torres, AN., et al. 2005. Virology. 332: 272-83. PMID: 15661159
6. Shedding of feline leukemia virus RNA in saliva is a consistent feature in viremic cats.  |  Gomes-Keller, MA., et al. 2006. Vet Microbiol. 112: 11-21. PMID: 16303261
7. Rapid detection of feline leukemia virus provirus integration into feline genomic DNA.  |  Cattori, V., et al. 2006. Mol Cell Probes. 20: 172-81. PMID: 16488115
8. Clearance of feline leukemia virus from persistently infected pet cats treated by extracorporeal immunoadsorption is correlated with an enhanced antibody response to FeLV gp 70.  |  Snyder, HW., et al. 1984. J Immunol. 132: 1538-43. PMID: 6319496
9. Appearance of cytotoxic antibody to viral gp70 on feline lymphoma cells (FL-74) in cats during ex vivo immunoadsorption therapy: quantitation, characterization, and association with remission of disease and disappearance of viremia.  |  Liu, WT., et al. 1984. Proc Natl Acad Sci U S A. 81: 3516-20. PMID: 6328520

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FeLV p27 Antibody (PF12J-10A) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FeLV p27 Antibody (PF12J-10A) Specifications

Alternate Product Name: FeLV p27

Product Clone Name: PF12J-10A

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: FeLV p27

Epitope Species: FeLV

Product Reactivity/Detection: p27 core

Species Reactivity/Detection: FeLV

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, IHC(P)

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for FeLV p27 Antibody (PF12J-10A): N/A