
Elf-4 Antibody (F-11) is a mouse monoclonal IgG2b light chain antibody that detects Elf-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Elf-4, also known as myeloid Elf-1-like factor or MEF, is a 663 amino acid member of the Ets-1 family of transcription factors, characterized by a conserved DNA binding domain that plays a crucial role in regulating cellular processes such as proliferation, differentiation, and angiogenesis. Elf-4 (F-11) antibody targets a protein primarily localized in the nucleus and highly expressed in the placenta and myeloid leukemia cells, while exhibiting lower expression levels in tissues such as the lung, heart, thymus, spleen, colon, ovary, and peripheral blood lymphocytes. Notably, anti-Elf-4 antibody (F-11) recognizes a protein instrumental in activating the promoters of hematopoietic growth factor genes, including GM-CSF, IL-3, and IL-8, and has also been implicated in the activation of the Perforin 1 promoter in natural killer (NK) cells, highlighting its potential role in tumorigenesis. Elf-4 monoclonal antibody (F-11) versatility in various applications makes this reagent an essential tool for researchers studying the intricate functions of this important transcription factor.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Elf-4 Antibody (F-11) | sc-390689 | 200 µg/ml | $322.00 | |||
Elf-4 Antibody (F-11): m-IgGκ BP-HRP Bundle | sc-535638 | 200 µg Ab; 40 µg BP | $361.00 | |||
Elf-4 Antibody (F-11) X | sc-390689 X | 200 µg/0.1 ml | $322.00 |