E2F-4 Antibody (WUF10): sc-69686
- E2F-4 Antibody (WUF10) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against recombinant E2F-4 of human origin
- recommended for detection of E2F-4 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See E2F-4 (D-7): sc-398543 for E2F-4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for E2F-4 Antibody (WUF10) for WB and IHC(P) applications. These reagents are now offered in bundles with E2F-4 Antibody (WUF10) (see ordering information below).
E2F-4 Antibody (WUF10) is a mouse monoclonal IgG1 antibody that detects E2F-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. E2F-4 is a crucial member of the E2F family of transcription factors, which play a significant role in regulating the cell cycle, particularly during the transition from the G1 phase to the S phase. This regulation is vital for proper cell proliferation and differentiation, as dysregulation of E2F activity can lead to uncontrolled cell growth and is often implicated in various cancers. E2F-4 functions by forming heterodimers with the DP-1 protein, creating an active transcriptional complex that binds to specific DNA sequences to regulate the expression of genes essential for cell cycle progression. The interaction of E2F-4 with other proteins, including retinoblastoma protein (Rb), further underscores E2F-4′s importance in cell cycle control, as Rb acts as a tumor suppressor that inhibits E2F activity under normal conditions. Anti-E2F-4 antibody (WUF10) serves as an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying tumorigenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E2F-4 Antibody (WUF10) | sc-69686 | 200 µg/ml | $322.00 | |||
E2F-4 Antibody (WUF10): m-IgG Fc BP-HRP Bundle | sc-539221 | 200 µg Ab; 10 µg BP | $361.00 | |||
E2F-4 Antibody (WUF10): m-IgG1 BP-HRP Bundle | sc-541335 | 200 µg Ab; 20 µg BP | $361.00 |