E2F-4 Antibody (TFE-42): sc-56668
- E2F-4 Antibody (TFE-42) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against full length E2F-4 of human origin
- recommended for detection of E2F-4 of mouse, rat and human origin by WB, IP, IF and ELISA
- See E2F-4 (D-7): sc-398543 for E2F-4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for E2F-4 Antibody (TFE-42) for WB applications. These reagents are now offered in bundles with E2F-4 Antibody (TFE-42) (see ordering information below).
E2F-4 Antibody (TFE-42) is a mouse monoclonal IgG1 antibody that detects E2F-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). E2F-4 plays a crucial role in the regulation of the cell cycle, particularly in the transition from the G1 phase to the S phase, by forming heterodimers with the DP-1 protein to create an active E2F transcriptional regulatory complex. This complex is essential for the transcriptional activation of genes that are vital for DNA synthesis and cell proliferation. Dysregulation of E2F-4 can lead to uncontrolled cell growth and is implicated in various cancers, making E2F-4 a significant target for therapeutic intervention. The ability of E2F-4 to interact with other members of the E2F family, such as E2F-1, E2F-2, and E2F-3, further underscores E2F-4′s importance in maintaining proper cell cycle control and highlights E2F-4′s potential as a biomarker in cancer research. Anti-E2F-4 antibody (TFE-42) is an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying tumorigenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E2F-4 Antibody (TFE-42) | sc-56668 | 200 µg/ml | $322.00 | |||
E2F-4 Antibody (TFE-42): m-IgG Fc BP-HRP Bundle | sc-537112 | 200 µg Ab; 10 µg BP | $361.00 | |||
E2F-4 Antibody (TFE-42): m-IgGκ BP-HRP Bundle | sc-534304 | 200 µg Ab; 40 µg BP | $361.00 |