cytoglobin Antibody (G-2): sc-365247
- cytoglobin Antibody (G-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-190 representing full length cytoglobin of human origin
- recommended for detection of cytoglobin of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for cytoglobin Antibody (G-2) for WB applications. These reagents are now offered in bundles with cytoglobin Antibody (G-2) (see ordering information below).
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Cytoglobin Antibody (G-2) is a mouse monoclonal IgG1 antibody that detects cytoglobin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cytoglobin plays a crucial role in oxygen transport and storage, acting as a vital component in the diffusion of oxygen through various tissues while also serving as a scavenger for reactive oxygen species, including nitric oxide. Anti-cytoglobin antibody (G-2) is particularly important for studying protective functions during oxidative stress, which is essential for maintaining cellular health and function. Cytoglobin is a hexacoordinate hemoglobin that exhibits less than 30% identity with other human hemoglobins, highlighting its unique structure and function. Cytoglobin monoclonal antibody (G-2) enables research across diverse tissues, including fibroblasts and nerve cell populations, underscoring cytoglobin′s significance in various physiological processes.
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cytoglobin Antibody (G-2) References:
- Neuroglobin and cytoglobin in search of their role in the vertebrate globin family. | Hankeln, T., et al. 2005. J Inorg Biochem. 99: 110-9. PMID: 15598495
- Hypoxia/ischemia and the regulation of neuroglobin and cytoglobin expression. | Fordel, E., et al. 2004. IUBMB Life. 56: 681-7. PMID: 15804832
- Regulation and role of neuroglobin and cytoglobin under hypoxia. | Burmester, T., et al. 2007. Adv Exp Med Biol. 618: 169-80. PMID: 18269196
- Cytoglobin as a Biomarker in Cancer: Potential Perspective for Diagnosis and Management. | Bholah, TC., et al. 2015. Biomed Res Int. 2015: 824514. PMID: 26339645
- Discovery of cytoglobin and its roles in physiology and pathology of hepatic stellate cells. | Yoshizato, K., et al. 2016. Proc Jpn Acad Ser B Phys Biol Sci. 92: 77-97. PMID: 26972599
- Cytoglobin at the Crossroads of Vascular Remodeling. | Amdahl, MB., et al. 2017. Arterioscler Thromb Vasc Biol. 37: 1803-1805. PMID: 28954806
- Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin. | Zweier, JL. and Ilangovan, G. 2020. Antioxid Redox Signal. 32: 1172-1187. PMID: 31880165
- Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis. | Thuy, LTT., et al. 2020. Clin Mol Hepatol. 26: 280-293. PMID: 32492766
- Cytoglobin protects cancer cells from apoptosis by regulation of mitochondrial cardiolipin. | Thorne, LS., et al. 2021. Sci Rep. 11: 985. PMID: 33441751
- Cytoglobin regulates NO-dependent cilia motility and organ laterality during development. | Rochon, ER., et al. 2023. Nat Commun. 14: 8333. PMID: 38097556
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cytoglobin Antibody (G-2) | sc-365247 | 200 µg/ml | $322.00 | |||
cytoglobin Antibody (G-2): m-IgG Fc BP-HRP Bundle | sc-540320 | 200 µg Ab; 10 µg BP | $361.00 | |||
cytoglobin Antibody (G-2): m-IgG1 BP-HRP Bundle | sc-542040 | 200 µg Ab; 20 µg BP | $361.00 |