c-Rel Antibody (G-7): sc-365720

c-Rel Antibody (G-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects c-Rel protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). c-Rel (G-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. c-Rel protein plays a pivotal role in the immune response as a member of the NFκB family of transcription factors, which are essential for regulating the expression of genes involved in inflammation, cell survival, and immune responses. c-Rel protein is primarily located in the cytoplasm of resting cells and translocates to the nucleus upon activation, where c-Rel binds to specific DNA sequences to initiate transcription. This dynamic localization is crucial for the timely regulation of immune responses, as c-Rel allows for rapid activation of genes necessary for T cell proliferation and differentiation. c-Rel protein′s interaction with other NFκB family members, such as p65 and p50, enhances transcriptional activity, making c-Rel a key player in the orchestration of immune signaling pathways. Understanding c-Rel protein function and localization is vital for elucidating c-Rel′s role in various diseases, including autoimmune disorders and cancers, where dysregulation of NFκB signaling can lead to pathological outcomes.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-c-Rel Antibody (G-7) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-c-Rel Antibody (G-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

c-Rel Antibody (G-7) Specifications

Alternate Product Name: c-Rel

Product Clone Name: G-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 489-524

Epitope Target: c-Rel

Epitope Species: mouse

Product Reactivity/Detection: c-Rel p75

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for c-Rel Antibody (G-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent

The preferred c-Rel antibody is c-Rel Antibody (B-6): sc-6955.