Zinc finger protein 519 (ZNF519) is a part of the zinc finger protein family, which is one of the largest families of transcription factors in eukaryotic organisms. The term "zinc finger" describes the finger-like protrusions that a zinc ion can create by coordinating with cysteine and histidine residues within the protein structure. These structures enable the protein to interact with DNA, RNA, or other proteins, typically conferring the ability to bind to specific DNA sequences and regulate gene expression. ZNF519 likely contains multiple zinc finger domains that facilitate its binding to DNA in a sequence-specific manner. This feature allows ZNF519 to act as a transcriptional regulator controlling the expression of genes involved in various biological processes such as development, differentiation, and metabolism.
ZNF519, like other zinc finger proteins, may be involved in intricate networks of gene regulation, capable of activating or repressing target genes depending on the cellular context. Additionally, it could interact with other proteins to form complexes that modulate its binding specificity or transcriptional activity. Zinc finger proteins often participate in chromatin remodeling, DNA repair, and apoptosis, which are essential for maintaining cellular integrity and responding to environmental stressors.Understanding the exact role of ZNF519 would require in-depth studies, including its expression patterns, target genes, and binding partners. This information is crucial for elucidating its function in normal physiological processes and determining whether it plays a role in the pathogenesis of diseases such as cancer or developmental disorders. Due to the diverse nature of zinc finger proteins, ZNF519 may possess unique attributes that distinguish it from other members of its family, highlighting the importance of targeted research into its specific biological activities.
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| 製品名 | CAS # | カタログ # | 数量 | 価格 | 引用文献 | レーティング |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNAメチル基転移酵素阻害剤であって、ZNF519のようなジンクフィンガータンパク質をコードする遺伝子を含む遺伝子の発現を変化させる可能性のあるもの。 | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
ヒストン脱アセチル化酵素阻害剤として働き、ジンクフィンガータンパク質の発現に影響を与える可能性がある。 | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
クロマチン構造と遺伝子発現に影響を与えるヒストン脱アセチル化酵素阻害剤。 | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
別のヒストン脱アセチル化酵素阻害剤で、ZNF519の発現に影響を与える可能性がある。 | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
ZNFタンパク質におけるジンクフィンガーモチーフの構造的完全性に必須。 | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
複数のシグナル伝達経路に影響を与え、間接的にZNF519の機能に影響を与える可能性がある。 | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
遺伝子発現とタンパク質活性に影響を与えることが知られており、ZNF519に影響を与える可能性がある。 | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
様々なシグナル伝達経路に影響を与え、おそらくZNF519の活性に影響を与える。 | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
遺伝子発現とタンパク質機能を調節し、ZNF519に影響を与える可能性がある。 | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
遺伝子発現に影響を与え、ZNF519に影響を与える可能性がある。 | ||||||