Date published: 2026-1-12

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LOC646405 アクチベーター

LOC646405 is a provisional designation used in genomic databases for a gene locus that has not yet been fully characterized or may not correspond to a known protein-coding gene. This kind of designation is common in genomic annotation projects where automated computational tools predict the existence of a gene based on DNA sequences, but experimental evidence to confirm the gene's function, the existence of the protein, or its biological role is lacking or incomplete.

The "LOC" prefix indicates "locus," suggesting a specific location within the genome, while the numbers that follow serve as a unique identifier. In the case of LOC646405, it implies that this sequence is the 646,405th locus entered into a particular database. The annotation might be found in genomic sequencing projects such as the Human Genome Project or other organismal sequencing efforts.The characterization of such loci can involve various experimental approaches, including transcript profiling to detect RNA expression, proteomic studies to identify the protein product, and functional assays to determine the biological role of the protein. Additionally, comparative genomics can provide clues about the function of the protein by identifying homologous genes in other species.

製品名CAS #カタログ #数量価格引用文献レーティング

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

DNAメチル化酵素阻害剤であり、特定の遺伝子座における未知の遺伝子を含む遺伝子発現に影響を及ぼす可能性がある。

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

ヒストン脱アセチル化酵素阻害剤で、クロマチンリモデリングに影響を与え、遺伝子発現に影響を与える可能性がある。

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

ROCK阻害剤で、Rho GTPaseシグナル伝達経路に影響を及ぼす。

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

微小管を安定化させ、細胞分裂に影響を与え、様々なタンパク質の機能に影響を与える可能性がある。

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

細胞の成長と増殖の重要な調節因子であるmTORを阻害する。

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

プロテアソーム阻害剤で、タンパク質の分解と代謝に影響を及ぼす。

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

シクロフィリンと相互作用し、タンパク質のフォールディングと機能に影響を及ぼす。