LOC646405 is a provisional designation used in genomic databases for a gene locus that has not yet been fully characterized or may not correspond to a known protein-coding gene. This kind of designation is common in genomic annotation projects where automated computational tools predict the existence of a gene based on DNA sequences, but experimental evidence to confirm the gene's function, the existence of the protein, or its biological role is lacking or incomplete.
The "LOC" prefix indicates "locus," suggesting a specific location within the genome, while the numbers that follow serve as a unique identifier. In the case of LOC646405, it implies that this sequence is the 646,405th locus entered into a particular database. The annotation might be found in genomic sequencing projects such as the Human Genome Project or other organismal sequencing efforts.The characterization of such loci can involve various experimental approaches, including transcript profiling to detect RNA expression, proteomic studies to identify the protein product, and functional assays to determine the biological role of the protein. Additionally, comparative genomics can provide clues about the function of the protein by identifying homologous genes in other species.
| 製品名 | CAS # | カタログ # | 数量 | 価格 | 引用文献 | レーティング |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNAメチル化酵素阻害剤であり、特定の遺伝子座における未知の遺伝子を含む遺伝子発現に影響を及ぼす可能性がある。 | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
ヒストン脱アセチル化酵素阻害剤で、クロマチンリモデリングに影響を与え、遺伝子発現に影響を与える可能性がある。 | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK阻害剤で、Rho GTPaseシグナル伝達経路に影響を及ぼす。 | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
微小管を安定化させ、細胞分裂に影響を与え、様々なタンパク質の機能に影響を与える可能性がある。 | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
細胞の成長と増殖の重要な調節因子であるmTORを阻害する。 | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
プロテアソーム阻害剤で、タンパク質の分解と代謝に影響を及ぼす。 | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
シクロフィリンと相互作用し、タンパク質のフォールディングと機能に影響を及ぼす。 | ||||||