FDC-SP activators belong to a specific chemical class designed to modulate the function of FDC-SP, a protein or molecule with a particular role in biological systems. FDC-SP, which stands for Follicular Dendritic Cell-Secreted Protein, plays an important role within the immune system and lymphoid tissues. It is typically produced and secreted by follicular dendritic cells, specialized cells found in lymphoid follicles of secondary lymphoid organs like lymph nodes, spleen, and tonsils. The primary function of FDC-SP is related to its involvement in the formation and maintenance of germinal centers within lymphoid tissues. Germinal centers are critical for the development of adaptive immune responses, including the production of antibodies by B cells and the generation of memory B cells.
Activators of FDC-SP may influence the protein's secretion or function, potentially affecting the dynamics of germinal center formation and the immune response. Understanding how FDC-SP activators work and their effects on immune processes is a subject of interest in immunology research. These activators could provide insights into the regulation of immune responses and the development of strategies to enhance or modulate the immune system's activity when needed.
製品名 | CAS # | カタログ # | 数量 | 価格 | 引用文献 | レーティング |
---|---|---|---|---|---|---|
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
リポ多糖(LPS)は、ヒト末梢血単核細胞(PBMC)においてFDC-SPの発現を誘導することが知られています。LPSは、I型サイトカインおよびケモカインの発現を誘導することが示されている濃度で機能し、自然免疫シグナルによる制御を示しています。 |