Date published: 2026-5-25

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DNA pol ι Antibodies

Santa Cruz Biotechnology provides a broad selection of DNA pol ι Antibodies for investigating the role of this crucial enzyme in DNA replication and repair. DNA pol ι Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA polymerase iota (DNA pol ι) is a specialized enzyme that plays a significant role in translesion synthesis, allowing cells to bypass DNA lesions during replication. This function is vital for maintaining genomic stability and preventing mutations that could lead to cancer. Understanding the activity and regulation of DNA pol ι is essential for elucidating mechanisms of DNA damage tolerance and repair pathways. DNA pol ι research has revealed important insights into cellular responses to DNA damage and potential therapeutic targets. Investigating DNA pol ι function has enhanced our understanding of cancer development and progression. Current research focuses on how DNA pol ι contributes to mutation prevention and DNA repair mechanisms. Santa Cruz Biotechnology monoclonal antibodies for DNA pol ι enable researchers worldwide to advance scientific understanding of DNA repair processes and cancer biology.

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DNA pol ι Antibodies

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DNA pol ι Antibody (NN7)

sc-101026mouse IgG3 κ616-716 (h)WB, IP, ELISAh
2
(3)

DNA pol ι CRISPR Knockout, HDR and Double Nickase Plasmids

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DNA pol ι CRISPR/Cas9 KO Plasmid (h)

sc-406351hGene KnockoutGFP0
(0)

DNA pol ι HDR Plasmid (h)

sc-406351-HDRhHomology Directed RepairPuromycin0
(0)

DNA pol ι siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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DNA pol ι siRNA (h)

sc-37785hGene SilencingN/A0
(0)

DNA pol ι shRNA Plasmid (h)

sc-37785-SHhGene SilencingPuromycin0
(0)

DNA pol ι shRNA (h) Lentiviral Particles

sc-37785-VhGene SilencingPuromycin0
(0)

DNA pol ι siRNA (m)

sc-37786mGene SilencingN/A0
(0)

DNA pol ι shRNA Plasmid (m)

sc-37786-SHmGene SilencingPuromycin0
(0)

DNA pol ι shRNA (m) Lentiviral Particles

sc-37786-VmGene SilencingPuromycin0
(0)