NAB2 Antibody (A-5): sc-398123
- NAB2 Antibody (A-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 489-516 at the C-terminus of NAB2 of human origin
- recommended for detection of NAB2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and porcine
- See NAB2 (1C4): sc-23867 for NAB2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NAB2 Antibody (A-5) for WB applications. These reagents are now offered in bundles with NAB2 Antibody (A-5) (see ordering information below).
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NAB2 Antibody (A-5) is a mouse monoclonal IgG1 antibody that detects NAB2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NAB2 is a crucial corepressor of the transcription factor Egr-1/NGFI-A, playing a significant role in the regulation of gene expression and cellular processes. NAB2 is primarily localized in the nucleus, where NAB2 is essential for modulating the activity of NGFI-A, thereby influencing vital functions such as cell division, differentiation, and apoptosis. NAB2′s interaction with NGFI-A is mediated by its amino terminal NAB conserved domain 1 (NCB1), which is critical for binding, while its carboxy terminal NCD2 domain is responsible for its repressive function. NAB2 is located at chromosome 12q13.3-14.1, a genomic region frequently altered in various solid tumors, lipomas, and liposarcomas, highlighting NAB2′s potential importance in cancer biology. Anti-NAB2 antibody (A-5) is an invaluable tool for researchers investigating the intricate mechanisms of transcriptional regulation and the implications of NAB2 in disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAB2 Antibody (A-5) | sc-398123 | 200 µg/ml | $322.00 | |||
NAB2 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538371 | 200 µg Ab; 10 µg BP | $361.00 | |||
NAB2 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-535973 | 200 µg Ab; 40 µg BP | $361.00 | |||
NAB2 Antibody (A-5): m-IgG1 BP-HRP Bundle | sc-545665 | 200 µg Ab; 20 µg BP | $361.00 | |||
NAB2 (A-5) Neutralizing Peptide | sc-398123 P | 100 µg/0.5 ml | $69.00 |